日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

KRT17high/CXCL8+ Tumor Cells Display Both Classical and Basal Features and Regulate Myeloid Infiltration in the Pancreatic Cancer Microenvironment

KRT17high/CXCL8+ 肿瘤细胞表现出经典和基础特征并调节胰腺癌微环境中的髓系浸润

Eileen S Carpenter, Padma Kadiyala, Ahmed M Elhossiny, Samantha B Kemp, Jay Li, Nina G Steele, Rémy Nicolle, Zeribe C Nwosu, Julia Freeman, Henry Dai, Daniel Paglia, Wenting Du, Katelyn Donahue, Jacqueline Morales, Paola I Medina-Cabrera, Monica E Bonilla, Lindsey Harris, Stephanie The, Valerie Gunc

Potentiating the radiation-induced type I interferon antitumoral immune response by ATM inhibition in pancreatic cancer

通过抑制ATM增强胰腺癌中辐射诱导的I型干扰素抗肿瘤免疫反应

Qiang Zhang ,Long Jiang ,Weiwei Wang ,Amanda K Huber ,Victoria M Valvo ,Kassidy M Jungles ,Erin A Holcomb ,Ashley N Pearson ,Stephanie The ,Zhuwen Wang ,Leslie A Parsels ,Joshua D Parsels ,Daniel R Wahl ,Arvind Rao ,Vaibhav Sahai ,Theodore S Lawrence ,Michael D Green ,Meredith A Morgan

Complement C3d enables cell-mediated immunity capable of distinguishing spontaneously transformed from nontransformed cells

补体 C3d 可使细胞介导免疫区分自发转化细胞和非转化细胞

Jeffrey L Platt, Chong Zhao, Jeffrey Chicca, Matthew J Pianko, Joshua Han, Stephanie The, Arvind Rao, Evan T Keller, Mayara Garcia de Mattos Barbosa, Lwar Naing, Tracy Pasieka-Axenov, Lev Axenov, Simon Schaefer, Evan Farkash, Marilia Cascalho

Analysis of Donor Pancreata Defines the Transcriptomic Signature and Microenvironment of Early Neoplastic Lesions

供体胰腺的分析确定了早期肿瘤病变的转录组特征和微环境

Eileen S Carpenter #, Ahmed M Elhossiny #, Padma Kadiyala #, Jay Li, Jake McGue, Brian D Griffith, Yaqing Zhang, Jacob Edwards, Sarah Nelson, Fatima Lima, Katelyn L Donahue, Wenting Du, Allison C Bischoff, Danyah Alomari, Hannah R Watkoske, Michael Mattea, Stephanie The, Carlos E Espinoza, Meredith

Extrinsic KRAS Signaling Shapes the Pancreatic Microenvironment Through Fibroblast Reprogramming

外源性 KRAS 信号通过成纤维细胞重编程塑造胰腺微环境

Ashley Velez-Delgado, Katelyn L Donahue, Kristee L Brown, Wenting Du, Valerie Irizarry-Negron, Rosa E Menjivar, Emily L Lasse Opsahl, Nina G Steele, Stephanie The, Jenny Lazarus, Veerin R Sirihorachai, Wei Yan, Samantha B Kemp, Samuel A Kerk, Murali Bollampally, Sion Yang, Michael K Scales, Faith R

Apolipoprotein E Promotes Immune Suppression in Pancreatic Cancer through NF-κB-Mediated Production of CXCL1

载脂蛋白 E 通过 NF-κB 介导的 CXCL1 产生促进胰腺癌的免疫抑制

Samantha B Kemp, Eileen S Carpenter, Nina G Steele, Katelyn L Donahue, Zeribe C Nwosu, Amanda Pacheco, Ashley Velez-Delgado, Rosa E Menjivar, Fatima Lima, Stephanie The, Carlos E Espinoza, Kristee Brown, Daniel Long, Costas A Lyssiotis, Arvind Rao, Yaqing Zhang, Marina Pasca di Magliano, Howard C Cr

Inhibition of Hedgehog Signaling Alters Fibroblast Composition in Pancreatic Cancer

抑制 Hedgehog 信号通路会改变胰腺癌中成纤维细胞的组成

Nina G Steele # ,Giulia Biffi # ,Samantha B Kemp ,Yaqing Zhang ,Donovan Drouillard ,LiJyun Syu ,Yuan Hao ,Tobiloba E Oni ,Erin Brosnan ,Ela Elyada ,Abhishek Doshi ,Christa Hansma ,Carlos Espinoza ,Ahmed Abbas ,Stephanie The ,Valerie Irizarry-Negron ,Christopher J Halbrook ,Nicole E Franks ,Megan T Hoffman ,Kristee Brown ,Eileen S Carpenter ,Zeribe C Nwosu ,Craig Johnson ,Fatima Lima ,Michelle A Anderson ,Youngkyu Park ,Howard C Crawford ,Costas A Lyssiotis ,Timothy L Frankel ,Arvind Rao ,Filip Bednar ,Andrzej A Dlugosz ,Jonathan B Preall ,David A Tuveson ,Benjamin L Allen ,Marina Pasca di Magliano

The Gustatory Sensory G-Protein GNAT3 Suppresses Pancreatic Cancer Progression in Mice

味觉感觉蛋白 GNAT3 抑制小鼠胰腺癌进展

Megan T Hoffman, Samantha B Kemp, Daniel J Salas-Escabillas, Yaqing Zhang, Nina G Steele, Stephanie The, Daniel Long, Simone Benitz, Wei Yan, Robert F Margolskee, Filip Bednar, Marina Pasca di Magliano, Hui-Ju Wen, Howard C Crawford

Multimodal Mapping of the Tumor and Peripheral Blood Immune Landscape in Human Pancreatic Cancer

人类胰腺癌肿瘤和外周血免疫景观的多模态映射

Nina G Steele #, Eileen S Carpenter #, Samantha B Kemp #, Veerin R Sirihorachai #, Stephanie The, Lawrence Delrosario, Jenny Lazarus, El-Ad David Amir, Valerie Gunchick, Carlos Espinoza, Samantha Bell, Lindsey Harris, Fatima Lima, Valerie Irizarry-Negron, Daniel Paglia, Justin Macchia, Angel Ka Yan