Stephen B Howell相关文献与解析，生知库 | 链接生命科学的每一步

Exploiting the Receptor-Binding Domains of R-Spondin 1 to Target Leucine-Rich Repeat-Containin G-Coupled Protein Receptor 5-Expressing Stem Cells in Ovarian Cancer

利用 R-Spondin 1 的受体结合域靶向卵巢癌中表达亮氨酸富集重复序列的 G 偶联蛋白受体 5 的干细胞

期刊:Journal of Pharmacology and Experimental Therapeutics

doi:10.1124/jpet.122.001495

Clara Wong, Maria Carmen Mulero, Erika I Barth, Katherine Wang, Xiying Shang, Sanika Tikle, Catherine Rice, Dennis Gately, Stephen B Howell

Luxeptinib interferes with LYN-mediated activation of SYK and modulates BCR signaling in lymphoma

Luxeptinib 干扰 LYN 介导的 SYK 激活并调节淋巴瘤中的 BCR 信号传导

期刊:PLoS One

影响因子:2.9

doi:10.1371/journal.pone.0277003

Himangshu Sonowal, William G Rice, Stephen B Howell

Luxeptinib (CG-806) Targets FLT3 and Clusters of Kinases Operative in Acute Myeloid Leukemia

Luxeptinib (CG-806) 靶向作用于急性髓系白血病的 FLT3 和激酶簇

期刊:Molecular Cancer Therapeutics

影响因子:5.3

doi:10.1158/1535-7163.MCT-21-0832

William G Rice, Stephen B Howell, Hongying Zhang, Nasrin Rastgoo, Andrea Local, Stephen E Kurtz, Pierrette Lo, Daniel Bottomly, Beth Wilmot, Shannon K McWeeney, Brian J Druker, Jeffrey W Tyner

Securing the Payload, Finding the Cell, and Avoiding the Endosome: Peptide-Targeted, Fusogenic Porous Silicon Nanoparticles for Delivery of siRNA

确保有效载荷安全、找到细胞并避开内体：用于递送 siRNA 的肽靶向融合多孔硅纳米粒子

期刊:Advanced Materials

影响因子:27.4

doi:10.1002/adma.201902952

Byungji Kim, Si Sun, Judith A Varner, Stephen B Howell, Erkki Ruoslahti, Michael J Sailor

A tumor-penetrating peptide enhances circulation-independent targeting of peritoneal carcinomatosis

肿瘤穿透肽增强了非循环依赖性的腹膜癌病靶向性

期刊:Journal of Controlled Release

影响因子:10.5

doi:10.1016/j.jconrel.2015.06.009

Kazuki N Sugahara, Pablo Scodeller, Gary B Braun, Tatiana Hurtado de Mendoza, Chisato M Yamazaki, Michael D Kluger, Joji Kitayama, Edwin Alvarez, Stephen B Howell, Tambet Teesalu, Erkki Ruoslahti, Andrew M Lowy

肿瘤

发表日期：2015

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Claudin-4 controls the receptor tyrosine kinase EphA2 pro-oncogenic switch through β-catenin

Claudin-4 通过 β-catenin 控制受体酪氨酸激酶 EphA2 促癌开关

期刊:Cell Communication and Signaling

影响因子:8.2

doi:10.1186/s12964-014-0059-5

Xiying Shang, Xinjian Lin, Stephen B Howell

Characterization of a monoclonal antibody capable of reliably quantifying expression of human Copper Transporter 1 (hCTR1)

能够可靠量化人类铜转运蛋白 1 (hCTR1) 表达的单克隆抗体的表征

期刊:Journal of Trace Elements in Medicine and Biology

影响因子:3.6

doi:10.1016/j.jtemb.2013.12.003

Jacob F Quail, Cheng-Yu Tsai, Stephen B Howell

Copper influx transporter 1 is required for FGF, PDGF and EGF-induced MAPK signaling

铜流入转运蛋白 1 是 FGF、PDGF 和 EGF 诱导的 MAPK 信号传导所必需的

期刊:Biochemical Pharmacology

影响因子:5.3

doi:10.1016/j.bcp.2012.07.014

Cheng-Yu Tsai, J Cameron Finley, Sameh S Ali, Hemal H Patel, Stephen B Howell

Sec61β controls sensitivity to platinum-containing chemotherapeutic agents through modulation of the copper-transporting ATPase ATP7A

Sec61β 通过调节铜转运 ATPase ATP7A 来控制对含铂化疗药物的敏感性

期刊:Molecular Pharmacology

影响因子:3.2

doi:10.1124/mol.112.079822

Paolo B Abada, Christopher A Larson, Gerald Manorek, Preston Adams, Stephen B Howell

信号转导

发表日期：2012

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Preclinical Development of Tuspetinib for the Treatment of Acute Myeloid Leukemia

Tuspetinib 治疗急性髓系白血病的临床前开发

Exploiting the Receptor-Binding Domains of R-Spondin 1 to Target Leucine-Rich Repeat-Containin G-Coupled Protein Receptor 5-Expressing Stem Cells in Ovarian Cancer

利用 R-Spondin 1 的受体结合域靶向卵巢癌中表达亮氨酸富集重复序列的 G 偶联蛋白受体 5 的干细胞

Luxeptinib interferes with LYN-mediated activation of SYK and modulates BCR signaling in lymphoma

Luxeptinib 干扰 LYN 介导的 SYK 激活并调节淋巴瘤中的 BCR 信号传导

Luxeptinib (CG-806) Targets FLT3 and Clusters of Kinases Operative in Acute Myeloid Leukemia

Luxeptinib (CG-806) 靶向作用于急性髓系白血病的 FLT3 和激酶簇

Securing the Payload, Finding the Cell, and Avoiding the Endosome: Peptide-Targeted, Fusogenic Porous Silicon Nanoparticles for Delivery of siRNA

确保有效载荷安全、找到细胞并避开内体：用于递送 siRNA 的肽靶向融合多孔硅纳米粒子

A tumor-penetrating peptide enhances circulation-independent targeting of peritoneal carcinomatosis

肿瘤穿透肽增强了非循环依赖性的腹膜癌病靶向性

Claudin-4 controls the receptor tyrosine kinase EphA2 pro-oncogenic switch through β-catenin

Claudin-4 通过 β-catenin 控制受体酪氨酸激酶 EphA2 促癌开关

Characterization of a monoclonal antibody capable of reliably quantifying expression of human Copper Transporter 1 (hCTR1)

能够可靠量化人类铜转运蛋白 1 (hCTR1) 表达的单克隆抗体的表征

Copper influx transporter 1 is required for FGF, PDGF and EGF-induced MAPK signaling

铜流入转运蛋白 1 是 FGF、PDGF 和 EGF 诱导的 MAPK 信号传导所必需的

Sec61β controls sensitivity to platinum-containing chemotherapeutic agents through modulation of the copper-transporting ATPase ATP7A

Sec61β 通过调节铜转运 ATPase ATP7A 来控制对含铂化疗药物的敏感性