日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Human blood PIG-A mutation and micronucleated reticulocyte flow cytometric assays: Method optimization and evaluation of intra- and inter-subject variation

人类血液 PIG-A 突变和微核网织红细胞流式细胞术检测:方法优化以及受试者内和受试者间变异的评估

Dorothea K Torous, Svetlana L Avlasevich, Mona G Khattab, Ayesha Baig, Lawrence J Saubermann, Yuhchyau Chen, Jeffrey C Bemis, David P Lovell, Vernon E Walker, James T MacGregor, Stephen D Dertinger

Predictions of genotoxic potential, mode of action, molecular targets, and potency via a tiered multiflow® assay data analysis strategy

通过分层多流® 检测数据分析策略预测基因毒性潜力、作用方式、分子靶点和效力

Stephen D Dertinger, Andrew R Kraynak, Ryan P Wheeldon, Derek T Bernacki, Steven M Bryce, Nikki Hall, Jeffrey C Bemis, Sheila M Galloway, Patricia A Escobar, George E Johnson

Benchmark dose analyses of multiple genetic toxicity endpoints permit robust, cross-tissue comparisons of MutaMouse responses to orally delivered benzo[a]pyrene

通过对多个遗传毒性终点进行基准剂量分析,可以对 MutaMouse 对口服苯并[a]芘的反应进行稳健的跨组织比较

Alexandra S Long, John W Wills, Dorothy Krolak, Matthew Guo, Stephen D Dertinger, Volker M Arlt, Paul A White

Investigating the Generalizability of the MultiFlow ® DNA Damage Assay and Several Companion Machine Learning Models With a Set of 103 Diverse Test Chemicals

使用一组 103 种不同的测试化学品研究 MultiFlow ® DNA 损伤检测和几种配套机器学习模型的通用性

Steven M Bryce, Derek T Bernacki, Stephanie L Smith-Roe, Kristine L Witt, Jeffrey C Bemis, Stephen D Dertinger

Interlaboratory evaluation of a multiplexed high information content in vitro genotoxicity assay

多路复用高信息含量体外遗传毒性试验的实验室间评估

Steven M Bryce, Derek T Bernacki, Jeffrey C Bemis, Richard A Spellman, Maria E Engel, Maik Schuler, Elisabeth Lorge, Pekka T Heikkinen, Ulrike Hemmann, Véronique Thybaud, Sabrina Wilde, Nina Queisser, Andreas Sutter, Andreas Zeller, Melanie Guérard, David Kirkland, Stephen D Dertinger

Gamma radiation at a human relevant low dose rate is genotoxic in mice

与人类相关的低剂量率的伽马射线对小鼠有遗传毒性

Anne Graupner, Dag M Eide, Christine Instanes, Jill M Andersen, Dag A Brede, Stephen D Dertinger, Ole C Lind, Anicke Brandt-Kjelsen, Hans Bjerke, Brit Salbu, Deborah Oughton, Gunnar Brunborg, Ann K Olsen

Comparison of in vitro and in vivo clastogenic potency based on benchmark dose analysis of flow cytometric micronucleus data

根据流式细胞术微核数据的基准剂量分析比较体外和体内致染色体断裂效力

Jeffrey C Bemis, John W Wills, Steven M Bryce, Dorothea K Torous, Stephen D Dertinger, Wout Slob

Comparison of male versus female responses in the Pig-a mutation assay

Pig-a 突变试验中雄性与雌性反应的比较

Carson Labash, Svetlana L Avlasevich, Kristine Carlson, Dorothea K Torous, Ariel Berg, Jeffrey C Bemis, James T MacGregor, Stephen D Dertinger

Genotoxic effects of two-generational selenium deficiency in mouse somatic and testicular cells

两代硒缺乏对小鼠体细胞和睾丸细胞的遗传毒性作用

Anne Graupner, Christine Instanes, Jill M Andersen, Anicke Brandt-Kjelsen, Stephen D Dertinger, Brit Salbu, Gunnar Brunborg, Ann-Karin Olsen

Induction of Pig-a mutant erythrocytes in male and female rats exposed to 1,3-propane sultone, ethyl carbamate, or thiotepa

暴露于 1,3-丙烷磺内酯、氨基甲酸乙酯或噻替派的雄性和雌性大鼠中 Pig-a 突变红细胞的诱导

Carson Labash, Kristine Carlson, Svetlana L Avlasevich, Ariel Berg, Jeffrey C Bemis, James T MacGregor, Stephen D Dertinger