日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Delineation of metabolic responses of Npc1-/-nih mice lacking the cholesterol-esterifying enzyme SOAT2 to acute treatment with 2-hydroxypropyl-β-cyclodextrin

缺乏胆固醇酯化酶 SOAT2 的 Npc1-/-nih 小鼠对 2-羟丙基-β-环糊精急性治疗的代谢反应描述

Charina M Ramirez, Anna M Taylor, Adam M Lopez, Joyce J Repa, Stephen D Turley

Systemic administration of 2-hydroxypropyl-β-cyclodextrin to symptomatic Npc1-deficient mice slows cholesterol sequestration in the major organs and improves liver function

对有症状的 Npc1 缺陷小鼠全身施用 2-羟丙基-β-环糊精可减缓主要器官中胆固醇的封存并改善肝功能

Adam M Lopez, Sandi J Terpack, Kenneth S Posey, Benny Liu, Charina M Ramirez, Stephen D Turley

A suppressor screen in Mecp2 mutant mice implicates cholesterol metabolism in Rett syndrome

Mecp2 突变小鼠的抑制筛选表明胆固醇代谢与雷特综合征有关

Christie M Buchovecky, Stephen D Turley, Hannah M Brown, Stephanie M Kyle, Jeffrey G McDonald, Benny Liu, Andrew A Pieper, Wenhui Huang, David M Katz, David W Russell, Jay Shendure, Monica J Justice

Multiple mechanisms limit the accumulation of unesterified cholesterol in the small intestine of mice deficient in both ACAT2 and ABCA1

多种机制限制了 ACAT2 和 ABCA1 缺陷小鼠小肠中未酯化胆固醇的积累

Stephen D Turley, Mark A Valasek, Joyce J Repa, John M Dietschy

Liver X receptor activation enhances cholesterol loss from the brain, decreases neuroinflammation, and increases survival of the NPC1 mouse

肝脏 X 受体激活可促进大脑胆固醇流失、减少神经炎症并提高 NPC1 小鼠的存活率

Joyce J Repa, Hao Li, Tamy C Frank-Cannon, Mark A Valasek, Stephen D Turley, Malú G Tansey, John M Dietschy