日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Classical swine fever virus Npro antagonises IRF3 to prevent IFN-independent TLR3 and RIG-I-mediated apoptosis

猪瘟病毒 Npro 拮抗 IRF3 以阻止 IFN 独立的 TLR3 和 RIG-I 介导的细胞凋亡

Samuel Hardy, Ben Jackson, Stephen Goodbourn, Julian Seago

Chicken interferome: avian interferon-stimulated genes identified by microarray and RNA-seq of primary chick embryo fibroblasts treated with a chicken type I interferon (IFN-α)

鸡干扰组:通过用鸡 I 型干扰素 (IFN-α) 处理的原代鸡胚胎成纤维细胞的微阵列和 RNA 测序鉴定的禽干扰素刺激基因

Efstathios S Giotis, Rebecca C Robey, Natalie G Skinner, Christopher D Tomlinson, Stephen Goodbourn, Michael A Skinner

Genetic screen of a library of chimeric poxviruses identifies an ankyrin repeat protein involved in resistance to the avian type I interferon response

嵌合痘病毒库的遗传筛选鉴定出一种参与抵抗禽 I 型干扰素反应的锚蛋白重复蛋白

Karen Buttigieg, Stephen M Laidlaw, Craig Ross, Marc Davies, Stephen Goodbourn, Michael A Skinner

LGP2 plays a critical role in sensitizing mda-5 to activation by double-stranded RNA

LGP2 在使 mda-5 对双链 RNA 激活敏感方面起着关键作用

Kay S Childs, Richard E Randall, Stephen Goodbourn

STAT2 deficiency and susceptibility to viral illness in humans

STAT2 缺乏与人类易患病毒性疾病

Sophie Hambleton, Stephen Goodbourn, Dan F Young, Paul Dickinson, Siti M B Mohamad, Manoj Valappil, Naomi McGovern, Andrew J Cant, Scott J Hackett, Peter Ghazal, Neil V Morgan, Richard E Randall

Paramyxovirus V proteins interact with the RNA Helicase LGP2 to inhibit RIG-I-dependent interferon induction

副粘病毒 V 蛋白与 RNA 解旋酶 LGP2 相互作用,抑制 RIG-I 依赖性干扰素诱导

Kay Childs, Richard Randall, Stephen Goodbourn

The African swine fever virus DP71L protein recruits the protein phosphatase 1 catalytic subunit to dephosphorylate eIF2alpha and inhibits CHOP induction but is dispensable for these activities during virus infection

非洲猪瘟病毒 DP71L 蛋白募集蛋白磷酸酶 1 催化亚基,使 eIF2alpha 去磷酸化,并抑制 CHOP 诱导,但在病毒感染期间,这些活动是可有可无的

Fuquan Zhang, Alice Moon, Kay Childs, Stephen Goodbourn, Linda K Dixon

The NPro product of bovine viral diarrhea virus inhibits DNA binding by interferon regulatory factor 3 and targets it for proteasomal degradation

牛病毒性腹泻病毒的 NPro 产物可抑制干扰素调节因子 3 的 DNA 结合,并将其作为蛋白酶体降解的目标

Louise Hilton, Kartykayan Moganeradj, Gang Zhang, Yun-Hsiang Chen, Richard E Randall, John W McCauley, Stephen Goodbourn