日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

The synthetic lethal interaction between CDS1 and CDS2 is a vulnerability in uveal melanoma and across multiple tumor types.

CDS1 和 CDS2 之间的合成致死相互作用是葡萄膜黑色素瘤以及多种肿瘤类型的弱点

Chan Pui Ying, Alexander Diana, Mehta Ishan, Matsuyama Larissa Satiko Alcantara Sekimoto, Harle Victoria, Olvera-León Rebeca, Park Jun Sung, Arriaga-González Fernanda G, van der Weyden Louise, Cheema Saamin, Iyer Vivek, Offord Victoria, Barneda David, Hawkins Phillip T, Stephens Len, Kozik Zuza, Woods Michael, Wong Kim, Balmus Gabriel, Vinceti Alessandro, Thompson Nicola A, Del Castillo Velasco-Herrera Martin, Wessels Lodewyk, van de Haar Joris, Gonçalves Emanuel, Sinha Sanju, Vázquez-Cruz Martha Estefania, Bisceglia Luisa, Raimondi Francesco, Choudhary Jyoti, Patiyal Sumeet, Venkatesh Anjan, Iorio Francesco, Ryan Colm J, Adams David J

Liver gene expression and its rewiring in hepatic steatosis are controlled by PI3Kα-dependent hepatocyte signaling.

肝脏基因表达及其在肝脂肪变性中的重编程受 PI3Kα 依赖性肝细胞信号传导控制

Régnier Marion, Polizzi Arnaud, Fougeray Tiffany, Fougerat Anne, Perrier Prunelle, Anderson Karen, Lippi Yannick, Smati Sarra, Lukowicz Céline, Lasserre Frédéric, Fouche Edwin, Huillet Marine, Rives Clémence, Tramunt Blandine, Naylies Claire, Garcia Géraldine, Rousseau-Bacquié Elodie, Bertrand-Michel Justine, Canlet Cécile, Chevolleau-Mege Sylvie, Debrauwer Laurent, Heymes Christophe, Burcelin Rémy, Levade Thierry, Gourdy Pierre, Wahli Walter, Blum Yuna, Gamet-Payrastre Laurence, Ellero-Simatos Sandrine, Guillermet-Guibert Julie, Hawkins Phillip, Stephens Len, Postic Catherine, Montagner Alexandra, Loiseau Nicolas, Guillou Hervé

ARFs get the BioID treatment: what have we been missing?

ARF 接受 BioID 处理:我们错过了什么?

Barneda, David; Stephens, Len; Hawkins, Phillip

How is the acyl chain composition of phosphoinositides created and does it matter?

磷酸肌醇的酰基链组成是如何形成的?它重要吗?

Barneda, David; Cosulich, Sabina; Stephens, Len; Hawkins, Phillip

Compensation between CSF1R+ macrophages and Foxp3+ Treg cells drives resistance to tumor immunotherapy

CSF1R+巨噬细胞和Foxp3+调节性T细胞之间的补偿作用驱动肿瘤免疫治疗耐药性

Gyori, David; Lim, Ee Lyn; Grant, Francis M; Spensberger, Dominik; Roychoudhuri, Rahul; Shuttleworth, Stephen J; Okkenhaug, Klaus; Stephens, Len R; Hawkins, Phillip T

The Inositol-3-Phosphate Synthase Biosynthetic Enzyme Has Distinct Catalytic and Metabolic Roles.

肌醇-3-磷酸合成酶生物合成酶具有独特的催化和代谢作用

Frej Anna D, Clark Jonathan, Le Roy Caroline I, Lilla Sergio, Thomason Peter A, Otto Grant P, Churchill Grant, Insall Robert H, Claus Sandrine P, Hawkins Phillip, Stephens Len, Williams Robin S B

More paths to PI3Kγ

更多通往PI3Kγ的途径

Stephens, Len; Hawkins, Phillip

Phosphoinositide 3-OH kinase regulates integrin-dependent processes in neutrophils by signaling through its effector ARAP3.

磷脂酰肌醇 3-OH 激酶通过其效应分子 ARAP3 发出信号,调节中性粒细胞中整合素依赖性过程

Gambardella Laure, Anderson Karen E, Jakus Zoltán, Kovács Miklós, Voigt Susann, Hawkins Phillip T, Stephens Len, Mócsai Attila, Vermeren Sonja

3D time series analysis of cell shape using Laplacian approaches

利用拉普拉斯方法对细胞形状进行三维时间序列分析

Du, Cheng-Jin; Hawkins, Phillip T; Stephens, Len R; Bretschneider, Till

GPCR activation of Ras and PI3Kc in neutrophils depends on PLCb2/b3 and the RasGEF RasGRP4

中性粒细胞中GPCR对Ras和PI3Kc的激活依赖于PLCβ2/β3和RasGEF RasGRP4。

Suire, Sabine; Lécureuil, Charlotte; Anderson, Karen E; Damoulakis, George; Niewczas, Izabella; Davidson, Keith; Guillou, Hervé; Pan, Dingxin; Jonathan Clark; Phillip T Hawkins; Stephens, Len