日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Phosphoproteomics of aged insulin-resistant bone identifies P70S6K phosphorylation of AFF4 as a gene-specific transcriptional regulator.

老年胰岛素抵抗骨骼的磷酸化蛋白质组学研究发现,AFF4 的 P70S6K 磷酸化是一种基因特异性转录调节因子。

Dutt Mriga, Liao Luoping, Kim Hani Jieun, Blazev Ronnie, Chan Audrey, Kore Hitesh, Bezawork-Geleta Ayenachew, Dong Li, Rivera Isela Sarahi, Wee Natalie K Y, Molendijk Jeffrey, Wong Julian P H, Haynes Vanessa R, Uribe Veronica, Lynch Gordon S, Smith Kelly A, Montgomery Magdalene K, Watt Matthew J, Yang Pengyi, Dodd Garron T, Vervoort Stephin J, Sims Natalie A, Parker Benjamin L

MORC2 is a phosphorylation-dependent DNA compaction machine.

MORC2 是一种磷酸化依赖的 DNA 压缩机器

Tan Winnie, Park Jeongveen, Venugopal Hariprasad, Lou Jieqiong, Dias Prabavi Shayana, Baldoni Pedro L, Moon Kyoung-Wook, Dite Toby A, Keenan Christine R, Gurzau Alexandra D, Lee Joonyoung, Johanson Timothy M, Leis Andrew, Yousef Jumana, Vaibhav Vineet, Dagley Laura F, Ang Ching-Seng, Corso Laura D, Davidovich Chen, Vervoort Stephin J, Smyth Gordon K, Blewitt Marnie E, Allan Rhys S, Hinde Elizabeth, D'Arcy Sheena, Ryu Je-Kyung, Shakeel Shabih

Protocol for double-crosslinking ChIP-seq to improve data quality and enhance detection of challenging chromatin targets

用于提高数据质量和增强对难检测染色质靶标的检测能力的双交联 ChIP-seq 方案

Yu Bao ,Roberta Cacioppo ,Alastair Crisp ,Ivan Shlamovitz ,Julian E Sale ,Ana Tufegdzic Vidakovic ,Stephin J Vervoort ,Andrew Zeller

Intracellular zinc protects tumours from T cell-mediated cytotoxicity

细胞内锌可保护肿瘤免受T细胞介导的细胞毒性作用

Lelliott, Emily J; Naddaf, Jonathan; Ganio, Katherine; Michie, Jessica; Wang, Shelly; Liu, Lin; Silke, Natasha; Ahn, Antonio; Ramsbottom, Kelly M; Brennan, Amelia J; Freeman, Andrew J; Goel, Shom; Vervoort, Stephin J; Kearney, Conor J; Beavis, Paul A; McDevitt, Christopher A; Silke, John; Oliaro, Jane

RNA kinetics influence the response to transcriptional perturbation in leukaemia cell lines

RNA动力学影响白血病细胞系对转录扰动的反应

Izabela Todorovski ,Mary-Jane Tsang ,Breon Feran ,Zheng Fan ,Sreeja Gadipally ,David Yoannidis ,Isabella Y Kong ,Stefan Bjelosevic ,Sarahi Rivera ,Olivia Voulgaris ,Magnus Zethoven ,Edwin D Hawkins ,Kaylene J Simpson ,Gisela Mir Arnau ,Anthony T Papenfuss ,Ricky W Johnstone ,Stephin J Vervoort

Epigenetic changes in inflammatory arthritis monocytes contribute to disease and can be targeted by JAK inhibition

炎症性关节炎单核细胞的表观遗传变化会导致疾病,可以通过 JAK 抑制来靶向治疗

Janneke G C Peeters, Arjan Boltjes, Rianne C Scholman, Stephin J Vervoort, Paul J Coffer, Michal Mokry, Sebastiaan J Vastert, Femke van Wijk, Jorg van Loosdregt

Inhibition of pyrimidine biosynthesis targets protein translation in acute myeloid leukemia

抑制嘧啶生物合成靶向急性髓系白血病中的蛋白质翻译

Joan So #, Alexander C Lewis #, Lorey K Smith, Kym Stanley, Rheana Franich, David Yoannidis, Lizzy Pijpers, Pilar Dominguez, Simon J Hogg, Stephin J Vervoort, Fiona C Brown, Ricky W Johnstone, Gabrielle McDonald, Danielle B Ulanet, Josh Murtie, Emily Gruber, Lev M Kats

Distinct modulation of IFNγ-induced transcription by BET bromodomain and catalytic P300/CBP inhibition in breast cancer

乳腺癌中 BET 溴结构域和催化 P300/CBP 抑制对 IFNγ 诱导转录的不同调节

Simon J Hogg #, Olga Motorna #, Conor J Kearney, Emily B Derrick, Imran G House, Izabela Todorovski, Madison J Kelly, Magnus Zethoven, Kenneth D Bromberg, Albert Lai, Paul A Beavis, Jake Shortt, Ricky W Johnstone #, Stephin J Vervoort #

The PP2A-Integrator-CDK9 axis fine-tunes transcription and can be targeted therapeutically in cancer

PP2A-Integrator-CDK9轴精细调控转录,可作为癌症治疗的靶点。

Stephin J Vervoort,Sarah A Welsh,Jennifer R Devlin,Elisa Barbieri,Deborah A Knight,Sarah Offley,Stefan Bjelosevic,Matteo Costacurta,Izabela Todorovski,Conor J Kearney,Jarrod J Sandow,Zheng Fan,Benjamin Blyth,Victoria McLeod,Joseph H A Vissers,Karolina Pavic,Ben P Martin,Gareth Gregory,Elena Demosthenous,Magnus Zethoven,Isabella Y Kong,Edwin D Hawkins,Simon J Hogg,Madison J Kelly,Andrea Newbold,Kaylene J Simpson,Otto Kauko,Kieran F Harvey,Michael Ohlmeyer,Jukka Westermarck,Nathanael Gray,Alessandro Gardini,Ricky W Johnstone

Antigen-driven EGR2 expression is required for exhausted CD8+ T cell stability and maintenance

抗原驱动的EGR2表达是耗竭CD8+ T细胞稳定性和维持所必需的

Mayura V Wagle ,Stephin J Vervoort ,Madison J Kelly ,Willem Van Der Byl ,Timothy J Peters ,Ben P Martin ,Luciano G Martelotto ,Simone Nüssing ,Kelly M Ramsbottom ,James R Torpy ,Deborah Knight ,Sinead Reading ,Kevin Thia ,Lisa A Miosge ,Debbie R Howard ,Renee Gloury ,Sarah S Gabriel ,Daniel T Utzschneider ,Jane Oliaro ,Jonathan D Powell ,Fabio Luciani ,Joseph A Trapani ,Ricky W Johnstone ,Axel Kallies ,Christopher C Goodnow # ,Ian A Parish #