日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Increased intestinal permeability exacerbates sepsis through reduced hepatic SCD-1 activity and dysregulated iron recycling

肠道通透性增加会通过降低肝脏 SCD-1 活性和铁循环失调加剧脓毒症

Manish Kumar, Aralia Leon Coria, Steve Cornick, Björn Petri, Shyamchand Mayengbam, Humberto B Jijon, France Moreau, Jane Shearer, Kris Chadee

VAMP8-mediated MUC2 mucin exocytosis from colonic goblet cells maintains innate intestinal homeostasis

VAMP8 介导的结肠杯状细胞 MUC2 黏蛋白外排维持先天肠道稳态

Steve Cornick, Manish Kumar, France Moreau, Herbert Gaisano, Kris Chadee

High MUC2 Mucin Expression and Misfolding Induce Cellular Stress, Reactive Oxygen Production, and Apoptosis in Goblet Cells

高 MUC2 黏蛋白表达和错误折叠会诱发杯状细胞的细胞应激、活性氧产生和细胞凋亡

Adelaide Tawiah, Steve Cornick, France Moreau, Hayley Gorman, Manish Kumar, Sameer Tiwari, Kris Chadee

The macrophage cytoskeleton acts as a contact sensor upon interaction with Entamoeba histolytica to trigger IL-1β secretion

巨噬细胞骨架在与溶组织内阿米巴相互作用时充当接触传感器,从而触发 IL-1β 分泌

Joëlle St-Pierre, France Moreau, Steve Cornick, Jeanie Quach, Sharmin Begum, Luz Aracely Fernandez, Hayley Gorman, Kris Chadee

Entamoeba histolytica Cysteine Proteinase 5 Evokes Mucin Exocytosis from Colonic Goblet Cells via αvβ3 Integrin

溶组织内阿米巴半胱氨酸蛋白酶 5 通过 αvβ3 整合素诱发结肠杯状细胞中的黏蛋白胞吐

Steve Cornick, France Moreau, Kris Chadee

The NLRP3 Inflammasome Is a Pathogen Sensor for Invasive Entamoeba histolytica via Activation of α5β1 Integrin at the Macrophage-Amebae Intercellular Junction

NLRP3 炎症小体通过激活巨噬细胞-阿米巴细胞间连接处的 α5β1 整合素,成为侵袭性溶组织内阿米巴的病原体传感器

Leanne Mortimer, France Moreau, Steve Cornick, Kris Chadee

Entamoeba histolytica contains an occludin-like protein that can alter colonic epithelial barrier function

溶组织内阿米巴含有一种类似闭合蛋白的蛋白质,可以改变结肠上皮屏障功能

Michael Goplen, Manigandan Lejeune, Steve Cornick, France Moreau, Kris Chadee