日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Epistatic interactions between NMD and TRP53 control progenitor cell maintenance and brain size

NMD和TRP53之间的上位性相互作用控制着祖细胞的维持和大脑大小。

Lin Lin ,Jingrong Zhao ,Naoto Kubota ,Zhelin Li ,Yi-Li Lam ,Lauren P Nguyen ,Lu Yang ,Sheela P Pokharel ,Steven M Blue ,Brian A Yee ,Renee Chen ,Gene W Yeo ,Chun-Wei Chen ,Liang Chen ,Sika Zheng

RBP Image Database: A resource for the systematic characterization of the subcellular distribution properties of human RNA binding proteins

RBP图像数据库:用于系统表征人类RNA结合蛋白亚细胞分布特性的资源

Louis Philip Benoit Bouvrette ,Xiaofeng Wang ,Jonathan Boulais ,Jian Kong ,Easin Uddin Syed ,Steven M Blue ,Lijun Zhan ,Sara Olson ,Rebecca Stanton ,Xintao Wei ,Brian Yee ,Eric L Van Nostrand ,Xiang-Dong Fu ,Christopher B Burge ,Brenton R Graveley ,Gene W Yeo ,Eric Lécuyer

Splicing factor SRSF1 deficiency in the liver triggers NASH-like pathology and cell death

肝脏中剪接因子 SRSF1 缺乏会引发 NASH 样病理和细胞死亡

Waqar Arif, Bhoomika Mathur, Michael F Saikali, Ullas V Chembazhi, Katelyn Toohill, You Jin Song, Qinyu Hao, Saman Karimi, Steven M Blue, Brian A Yee, Eric L Van Nostrand, Sushant Bangru, Grace Guzman, Gene W Yeo, Kannanganattu V Prasanth, Sayeepriyadarshini Anakk, Carolyn L Cummins, Auinash Kalsotr

Remodeling oncogenic transcriptomes by small molecules targeting NONO

利用靶向 NONO 的小分子重塑致癌转录组

Stefan G Kathman #, Seong Joo Koo #, Garrett L Lindsey #, Hsuan-Lin Her, Steven M Blue, Haoxin Li, Steffen Jaensch, Jarrett R Remsberg, Kay Ahn, Gene W Yeo, Brahma Ghosh, Benjamin F Cravatt

Transcriptome-wide identification of RNA-binding protein binding sites using seCLIP-seq

利用 seCLIP-seq 技术进行转录组范围内的 RNA 结合蛋白结合位点鉴定

Steven M Blue # ,Brian A Yee # ,Gabriel A Pratt ,Jasmine R Mueller ,Samuel S Park ,Alexander A Shishkin ,Anne C Starner ,Eric L Van Nostrand ,Gene W Yeo

A multi-scale map of cell structure fusing protein images and interactions

融合蛋白质图像和相互作用的细胞结构多尺度图

Yue Qin, Edward L Huttlin, Casper F Winsnes, Maya L Gosztyla, Ludivine Wacheul, Marcus R Kelly, Steven M Blue, Fan Zheng, Michael Chen, Leah V Schaffer, Katherine Licon, Anna Bäckström, Laura Pontano Vaites, John J Lee, Wei Ouyang, Sophie N Liu, Tian Zhang, Erica Silva, Jisoo Park, Adriana Pitea, Ja

The sustained expression of Cas9 targeting toxic RNAs reverses disease phenotypes in mouse models of myotonic dystrophy type 1

针对毒性 RNA 的 Cas9 持续表达可逆转 1 型强直性肌营养不良症小鼠模型中的疾病表型

Ranjan Batra #, David A Nelles #, Daniela M Roth, Florian Krach, Curtis A Nutter, Takahiro Tadokoro, James D Thomas, Łukasz J Sznajder, Steven M Blue, Haydee L Gutierrez, Patrick Liu, Stefan Aigner, Oleksandr Platoshyn, Atsushi Miyanohara, Martin Marsala, Maurice S Swanson, Gene W Yeo

Gain-of-function cardiomyopathic mutations in RBM20 rewire splicing regulation and re-distribute ribonucleoprotein granules within processing bodies

RBM20 获得功能性心肌病突变重新连接剪接调控并重新分配处理体内的核糖核蛋白颗粒

Aidan M Fenix #, Yuichiro Miyaoka #, Alessandro Bertero, Steven M Blue, Matthew J Spindler, Kenneth K B Tan, Juan A Perez-Bermejo, Amanda H Chan, Steven J Mayerl, Trieu D Nguyen, Caitlin R Russell, Paweena P Lizarraga, Annie Truong, Po-Lin So, Aishwarya Kulkarni, Kashish Chetal, Shashank Sathe, Nath

Loss of LUC7L2 and U1 snRNP subunits shifts energy metabolism from glycolysis to OXPHOS

LUC7L2 和 U1 snRNP 亚基的缺失导致能量代谢从糖酵解转向氧化磷酸化

Alexis A Jourdain,Bridget E Begg,Eran Mick,Hardik Shah,Sarah E Calvo,Owen S Skinner,Rohit Sharma,Steven M Blue,Gene W Yeo,Christopher B Burge,Vamsi K Mootha

fSHAPE, fSHAPE-eCLIP, and SHAPE-eCLIP probe transcript regions that interact with specific proteins

fSHAPE、fSHAPE-eCLIP 和 SHAPE-eCLIP 可探测与特定蛋白质相互作用的转录本区域。

Meredith Corley ,Ryan A Flynn ,Steven M Blue ,Brian A Yee ,Howard Y Chang ,Gene W Yeo