Theranostic pretargeted radioimmunotherapy of colorectal cancer xenografts in mice using picomolar affinity ⁸⁶Y- or ¹⁷⁷Lu-DOTA-Bn binding scFv C825/GPA33 IgG bispecific immunoconjugates
使用皮摩尔亲和力 ⁸⁶Y 或 ¹⁷⁷Lu-DOTA-Bn 结合 scFv C825/GPA33 IgG 双特异性免疫缀合物对小鼠结肠直肠癌异种移植进行治疗性预定位放射免疫治疗
期刊:European Journal of Nuclear Medicine and Molecular Imaging
影响因子:8.6
doi:10.1007/s00259-015-3254-8
Sarah M Cheal, Hong Xu, Hong-Fen Guo, Sang-Gyu Lee, Blesida Punzalan, Sandhya Chalasani, Edward K Fung, Achim Jungbluth, Pat B Zanzonico, Jorge A Carrasquillo, Joseph O'Donoghue, Peter M Smith-Jones, K Dane Wittrup, Nai-Kong V Cheung, Steven M Larson2
