日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

AMPK directly activates mTORC2 to promote cell survival during acute energetic stress

AMPK 直接激活 mTORC2 以促进急性能量应激期间的细胞存活

Dubek Kazyken, Brian Magnuson, Cagri Bodur, Hugo A Acosta-Jaquez, Deqiang Zhang, Xin Tong, Tammy M Barnes, Gabrielle K Steinl, Nicole E Patterson, Christopher H Altheim, Naveen Sharma, Ken Inoki, Gregory D Cartee, Dave Bridges, Lei Yin, Steven M Riddle, Diane C Fingar

The IKK-related kinase TBK1 activates mTORC1 directly in response to growth factors and innate immune agonists

IKK相关激酶TBK1在生长因子和先天免疫激动剂的刺激下直接激活mTORC1。

Cagri Bodur ,Dubek Kazyken ,Kezhen Huang ,Bilgen Ekim Ustunel ,Kate A Siroky ,Aaron Seth Tooley ,Ian E Gonzalez ,Daniel H Foley ,Hugo A Acosta-Jaquez ,Tammy M Barnes ,Gabrielle K Steinl ,Kae-Won Cho ,Carey N Lumeng ,Steven M Riddle ,Martin G Myers Jr ,Diane C Fingar

Pharmacological targeting of the pseudokinase Her3

假激酶 Her3 的药理靶向

Ting Xie, Sang Min Lim, Kenneth D Westover, Michael E Dodge, Dalia Ercan, Scott B Ficarro, Durga Udayakumar, Deepak Gurbani, Hyun Seop Tae, Steven M Riddle, Taebo Sim, Jarrod A Marto, Pasi A Jänne, Craig M Crews, Nathanael S Gray

Screening for novel LRRK2 inhibitors using a high-throughput TR-FRET cellular assay for LRRK2 Ser935 phosphorylation

使用高通量 TR-FRET 细胞检测法对 LRRK2 Ser935 磷酸化进行筛选,以寻找新型 LRRK2 抑制剂

Spencer B Hermanson, Coby B Carlson, Steven M Riddle, Jing Zhao, Kurt W Vogel, R Jeremy Nichols, Kun Bi

Homogenous fluorescent assays for characterizing small-molecule activators of AMP-activated protein kinase (AMPK)

均相荧光分析用于表征 AMP 活化蛋白激酶 (AMPK) 的小分子激活剂

Laurie J Reichling, Steven M Riddle, Baigen Mei, Rica Bruinsma, Tony A Goossens, Kristin G Huwiler, Mark Maffitt, Alyssa M G Newport, Xiao-Dong Qian, Carmen Ruttimann-Johnson, Kurt W Vogel