NOTCH3-targeted antibody drug conjugates regress tumors by inducing apoptosis in receptor cells and through transendocytosis into ligand cells
NOTCH3 靶向抗体药物偶联物通过诱导受体细胞凋亡和通过内吞作用进入配体细胞来消退肿瘤
期刊:Cell Reports Medicine
影响因子:11.7
doi:10.1016/j.xcrm.2021.100279
Kenneth G Geles, Yijie Gao, Andreas Giannakou, Latha Sridharan, Ting-Ting Yamin, Jing Zhang, Riyez Karim, Joel Bard, Nicole Piche-Nicholas, Manoj Charati, Andreas Maderna, Judy Lucas, Jonathon Golas, Magali Guffroy, Steven Pirie-Shepherd, Marc Roy, Jessie Qian, Tania Franks, Wenyan Zhong, Christophe
信号转导
细胞生物学
肿瘤
其它细胞
Apoptosis
Notch
