日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Inflamed Ulcerative Colitis Regions Associated With MRGPRX2-Mediated Mast Cell Degranulation and Cell Activation Modules, Defining a New Therapeutic Target

与MRGPRX2介导的肥大细胞脱颗粒和细胞活化模块相关的炎症性溃疡性结肠炎区域,定义了一个新的治疗靶点

Ernie Chen ,Ling-Shiang Chuang ,Mamta Giri ,Nicole Villaverde ,Nai-Yun Hsu ,Ksenija Sabic ,Sari Joshowitz ,Kyle Gettler ,Shikha Nayar ,Zhi Chai ,Isaac L Alter ,Colleen C Chasteau ,Ujunwa M Korie ,Siarhei Dzedzik ,Tin Htwe Thin ,Aayushee Jain ,Arden Moscati ,Gerardus Bongers ,Richard H Duerr ,Mark S Silverberg ,Steven R Brant ,John D Rioux ,Inga Peter ,L Philip Schumm ,Talin Haritunians ,Dermot P McGovern ,Yuval Itan ,Judy H Cho

Sestrin3 enhances macrophage-mediated generation of T helper 1 and T helper 17 cells in a mouse colitis model

Sestrin3 在小鼠结肠炎模型中增强巨噬细胞介导的 T 辅助细胞 1 和 T 辅助细胞 17 的生成

Liuqing Ge, Min Xu, Steven R Brant, Shaoping Liu, Chengliang Zhu, Jian Shang, Qiu Zhao, Feng Zhou

An increase in LRRK2 suppresses autophagy and enhances Dectin-1-induced immunity in a mouse model of colitis

在小鼠结肠炎模型中,LRRK2 的增加可抑制自噬并增强 Dectin-1 诱导的免疫力

Tetsuya Takagawa, Atsushi Kitani, Ivan Fuss, Beth Levine, Steven R Brant, Inga Peter, Masaki Tajima, Shiro Nakamura, Warren Strober

Genome-Wide Association Study Identifies African-Specific Susceptibility Loci in African Americans With Inflammatory Bowel Disease

全基因组关联研究确定了患有炎症性肠病的非洲裔美国人的非洲特异性易感基因位点

Steven R Brant, David T Okou, Claire L Simpson, David J Cutler, Talin Haritunians, Jonathan P Bradfield, Pankaj Chopra, Jarod Prince, Ferdouse Begum, Archana Kumar, Chengrui Huang, Suresh Venkateswaran, Lisa W Datta, Zhi Wei, Kelly Thomas, Lisa J Herrinton, Jan-Micheal A Klapproth, Antonio J Quiros,

The Pathogenic Role of NLRP3 Inflammasome Activation in Inflammatory Bowel Diseases of Both Mice and Humans

NLRP3 炎症小体激活在小鼠和人类炎症性肠病中的致病作用

Ling Liu, Ying Dong, Mei Ye, Shi Jin, Jianbo Yang, Maria E Joosse, Yu Sun, Jennifer Zhang, Mark Lazarev, Steven R Brant, Bashar Safar, Michael Marohn, Esteban Mezey, Xuhang Li

Compartment-specific immunity in the human gut: properties and functions of dendritic cells in the colon versus the ileum

人体肠道中的区域特异性免疫:结肠与回肠中树突状细胞的特性和功能

Elizabeth R Mann, David Bernardo, Nicholas R English, Jon Landy, Hafid O Al-Hassi, Simon T C Peake, Ripple Man, Timothy R Elliott, Henning Spranger, Gui Han Lee, Alyssa Parian, Steven R Brant, Mark Lazarev, Ailsa L Hart, Xuhang Li, Stella C Knight

Prom1 function in development, intestinal inflammation, and intestinal tumorigenesis

Prom1 在发育、肠道炎症和肠道肿瘤发生中的作用

Baktiar O Karim, Ki-Jong Rhee, Guosheng Liu, Kyuson Yun, Steven R Brant