日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Potential Plasma Proteins (LGALS9, LAMP3, PRSS8 and AGRN) as Predictors of Hospitalisation Risk in COVID-19 Patients

血浆蛋白(LGALS9、LAMP3、PRSS8 和 AGRN)可能作为 COVID-19 患者住院风险的预测指标

Thomas McLarnon, Darren McDaid, Seodhna M Lynch, Eamonn Cooper, Joseph McLaughlin, Victoria E McGilligan, Steven Watterson, Priyank Shukla, Shu-Dong Zhang, Magda Bucholc, Andrew English, Aaron Peace, Maurice O'Kane, Martin Kelly, Manav Bhavsar, Elaine K Murray, David S Gibson, Colum P Walsh, Anthony

Is systems pharmacology ready to impact upon therapy development? A study on the cholesterol biosynthesis pathway

系统药理学是否已准备好影响治疗发展?胆固醇生物合成途径研究

Helen E Benson, Steven Watterson, Joanna L Sharman, Chido P Mpamhanga, Andrew Parton, Christopher Southan, Anthony J Harmar, Peter Ghazal

An Interferon Regulated MicroRNA Provides Broad Cell-Intrinsic Antiviral Immunity through Multihit Host-Directed Targeting of the Sterol Pathway

干扰素调节的 microRNA 通过多重宿主定向靶向甾醇途径提供广泛的细胞内在抗病毒免疫

Kevin A Robertson, Wei Yuan Hsieh, Thorsten Forster, Mathieu Blanc, Hongjin Lu, Peter J Crick, Eylan Yutuc, Steven Watterson, Kimberly Martin, Samantha J Griffiths, Anton J Enright, Mami Yamamoto, Madapura M Pradeepa, Kimberly A Lennox, Mark A Behlke, Simon Talbot, Jürgen Haas, Lars Dölken, William

Rapid proteasomal elimination of 3-hydroxy-3-methylglutaryl-CoA reductase by interferon-γ in primary macrophages requires endogenous 25-hydroxycholesterol synthesis

原代巨噬细胞中干扰素-γ快速蛋白酶体消除3-羟基-3-甲基戊二酰辅酶A还原酶需要内源性25-羟基胆固醇的合成

Hongjin Lu, Simon Talbot, Kevin A Robertson, Steven Watterson, Thorsten Forster, Douglas Roy, Peter Ghazal

Host defense against viral infection involves interferon mediated down-regulation of sterol biosynthesis

宿主防御病毒感染涉及干扰素介导的甾醇生物合成下调

Mathieu Blanc, Wei Yuan Hsieh, Kevin A Robertson, Steven Watterson, Guanghou Shui, Paul Lacaze, Mizanur Khondoker, Paul Dickinson, Garwin Sing, Sara Rodríguez-Martín, Peter Phelan, Thorsten Forster, Birgit Strobl, Matthias Müller, Rudolph Riemersma, Timothy Osborne, Markus R Wenk, Ana Angulo, Peter