日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

The human branchpoint-interacting stem-loop sequence and structure regulates U2 snRNA expression, branchpoint recognition, and the transcriptome

人类分支点相互作用的茎环序列和结构调控U2 snRNA的表达、分支点识别和转录组。

Stevers, Meredith B; Katzman, Sol; Jurica, Melissa S

PRC2 loss impairs small cell lung cancer tumorigenesis and enhances sensitivity to G9a/GLP inhibition.

PRC2 缺失会损害小细胞肺癌的肿瘤发生,并增强对 G9a/GLP 抑制剂的敏感性。

Kopparam Jawahar, Chandrasekaran Gayathri, Hulsman Danielle, Pilger Liesa-Marie, Stevers Karen, Song Ji-Ying, Hernandez-Quiles Miguel, Dijkstra Jelmer, Badhai Jitendra, Landman Nick, Vermeulen Michiel, van Lohuizen Maarten

Tumour-wide RNA splicing aberrations generate actionable public neoantigens

肿瘤范围内的RNA剪接异常会产生可靶向的公共新抗原

Darwin W Kwok ,Nicholas O Stevers ,Iñaki Etxeberria ,Takahide Nejo ,Maggie Colton Cove ,Lee H Chen ,Jangham Jung ,Kaori Okada ,Senthilnath Lakshmanachetty ,Marco Gallus ,Abhilash Barpanda ,Chibo Hong ,Gary K L Chan ,Jerry Liu ,Samuel H Wu ,Emilio Ramos ,Akane Yamamichi ,Payal B Watchmaker ,Hirokazu Ogino ,Atsuro Saijo ,Aidan Du ,Nadia R Grishanina ,James Woo ,Aaron Diaz ,Shawn L Hervey-Jumper ,Susan M Chang ,Joanna J Phillips ,Arun P Wiita ,Christopher A Klebanoff ,Joseph F Costello ,Hideho Okada

The immortality mechanism of TERT promoter mutant cancers is self-reinforcing and reversible.

TERT启动子突变癌症的永生机制是自我增强且可逆的

Stevers Nicholas O, Kim Somang, Yuan Jimmy Bo, Barger Carter J, Hong Chibo, Lenzo Olivia, McKinney Andrew M, Wu Samuel H, Lee Yu Jin, Kwok Darwin W, Suwala Abigail K, Appin Christina L, Gordan John D, Molinaro Annette M, Song Jun S, Costello Joseph F

RBIO-10. Targeting telomere maintenance sensitizes group 3 medulloblastomas to ionizing radiation

RBIO-10。靶向端粒维持可增强3组髓母细胞瘤对电离辐射的敏感性

Reinier, Kyndaron; Chugh, Harpriya; Sargsyan, Arayik; Uy-Evanado, Audrey; Nakamura, Kotoka; Heckard, Elizabeth; Mathias, Marco; Grogan, Tristan; Elashoff, David; Salvucci, Angelo; Jui, Jonathan; Chugh, Sumeet S; Jung, Jangham; Yu, Bohyeon; Stevers, Nicholas; Jain, Abhinav; Rosatti, Emanuele; Costello, Joseph; Gallus, Marco; Gallus, Marco; Okada, Hideho; Nguyen, James; Ho, Winson; Lu, Rongze; Diaz, Aaron

The human branchpoint-interacting stem loop sequence and structure regulates U2 snRNA expression, branchpoint recognition, and transcriptome.

人类分支点相互作用茎环序列和结构调节 U2 snRNA 表达、分支点识别和转录组

Stevers Meredith B, Katzman Sol, Jurica Melissa S

Glioblastoma evolution and heterogeneity from a 3D whole-tumor perspective

从三维全肿瘤角度看胶质母细胞瘤的演化和异质性

Radhika Mathur, Qixuan Wang, Patrick G Schupp, Ana Nikolic, Stephanie Hilz, Chibo Hong, Nadia R Grishanina, Darwin Kwok, Nicholas O Stevers, Qiushi Jin, Mark W Youngblood, Lena Ann Stasiak, Ye Hou, Juan Wang, Takafumi N Yamaguchi, Marisa Lafontaine, Anny Shai, Ivan V Smirnov, David A Solomon, Susan

Whole tumor analysis reveals early origin of the TERT promoter mutation and intercellular heterogeneity in TERT expression

全肿瘤分析揭示了TERT启动子突变的早期起源以及TERT表达的细胞间异质性

Appin, Christina L; Hong, Chibo; Suwala, Abigail K; Hilz, Stephanie; Mathur, Radhika; Solomon, David A; Smirnov, Ivan V; Stevers, Nicholas O; Shai, Anny; Wang, Albert; Berger, Mitchel S; Chang, Susan M; Phillips, Joanna J; Costello, Joseph F

Telomeres in glioma: Maintenance mechanisms to therapeutic potential

胶质瘤中的端粒:从维持机制到治疗潜力

Stevers, Nicholas O; Costello, Joseph F

Challenges in the discovery of tumor-specific alternative splicing-derived cell-surface antigens in glioma

胶质瘤中肿瘤特异性选择性剪接衍生细胞表面抗原发现的挑战

Takahide Nejo,Lin Wang,Kevin K Leung,Albert Wang,Senthilnath Lakshmanachetty,Marco Gallus,Darwin W Kwok,Chibo Hong,Lee H Chen,Diego A Carrera,Michael Y Zhang,Nicholas O Stevers,Gabriella C Maldonado,Akane Yamamichi,Payal B Watchmaker,Akul Naik,Anny Shai,Joanna J Phillips,Susan M Chang,Arun P Wiita,James A Wells,Joseph F Costello,Aaron A Diaz,Hideho Okada