日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Human tau pathology transmits glial tau aggregates in the absence of neuronal tau

人类tau蛋白病理会在神经元tau蛋白缺失的情况下,导致神经胶质细胞中tau蛋白聚集。

Narasimhan, Sneha; Changolkar, Lakshmi; Riddle, Dawn M; Kats, Alexandra; Stieber, Anna; Weitzman, Sarah A; Zhang, Bin; Li, Zhiyong; Roberson, Erik D; Trojanowski, John Q; Lee, Virginia M Y

Progression of motor neuron disease is accelerated and the ability to recover is compromised with advanced age in rNLS8 mice

在rNLS8小鼠中,运动神经元疾病的进展会随着年龄的增长而加速,且恢复能力会下降。

Spiller, Krista J; Restrepo, Clark R; Khan, Tahiyana; Stieber, Anna M; Kwong, Linda K; Trojanowski, John Q; Lee, Virginia M-Y

Glioblastomas are composed of genetically divergent clones with distinct tumourigenic potential and variable stem cell-associated phenotypes

胶质母细胞瘤由遗传不同的克隆组成,具有不同的致瘤潜力和不同的干细胞相关表型

Daniel Stieber, Anna Golebiewska, Lisa Evers, Elizabeth Lenkiewicz, Nicolaas H C Brons, Nathalie Nicot, Anaïs Oudin, Sébastien Bougnaud, Frank Hertel, Rolf Bjerkvig, Laurent Vallar, Michael T Barrett, Simone P Niclou

TDP-43 skeins show properties of amyloid in a subset of ALS cases

在部分ALS病例中,TDP-43蛋白丝表现出淀粉样蛋白的特性。

Robinson, John L; Geser, Felix; Stieber, Anna; Umoh, Mfon; Kwong, Linda K; Van Deerlin, Vivianna M; Lee, Virginia M-Y; Trojanowski, John Q

TDP-43 in familial and sporadic frontotemporal lobar degeneration with ubiquitin inclusions.

TDP-43 在伴有泛素包涵体的家族性和散发性额颞叶变性中的作用

Cairns Nigel J, Neumann Manuela, Bigio Eileen H, Holm Ida E, Troost Dirk, Hatanpaa Kimmo J, Foong Chan, White Charles L 3rd, Schneider Julie A, Kretzschmar Hans A, Carter Deborah, Taylor-Reinwald Lisa, Paulsmeyer Katherine, Strider Jeffrey, Gitcho Michael, Goate Alison M, Morris John C, Mishra Manjari, Kwong Linda K, Stieber Anna, Xu Yan, Forman Mark S, Trojanowski John Q, Lee Virginia M-Y, Mackenzie Ian R A

Dysregulation of stathmin, a microtubule-destabilizing protein, and up-regulation of Hsp25, Hsp27, and the antioxidant peroxiredoxin 6 in a mouse model of familial amyotrophic lateral sclerosis

在家族性肌萎缩侧索硬化症小鼠模型中,微管去稳定蛋白stathmin的失调以及Hsp25、Hsp27和抗氧化剂过氧化物酶6的上调

Strey, Christoph W; Spellman, Daniel; Stieber, Anna; Gonatas, Jacqueline O; Wang, Xiaosong; Lambris, John D; Gonatas, Nicholas K