日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Identification of a leucine-mediated threshold effect governing macrophage mTOR signalling and cardiovascular risk

鉴定亮氨酸介导的阈值效应,控制巨噬细胞 mTOR 信号传导和心血管风险

Xiangyu Zhang #, Divya Kapoor #, Se-Jin Jeong, Alan Fappi, Jeremiah Stitham, Vasavi Shabrish, Ismail Sergin, Eman Yousif, Astrid Rodriguez-Velez, Yu-Sheng Yeh, Arick Park, Arif Yurdagul Jr, Oren Rom, Slava Epelman, Joel D Schilling, Marco Sardiello, Abhinav Diwan, Jaehyung Cho, Nathan O Stitziel, Al

Loss of Macrophage mTORC2 Drives Atherosclerosis via FoxO1 and IL-1β Signaling

巨噬细胞 mTORC2 的缺失通过 FoxO1 和 IL-1β 信号通路驱动动脉粥样硬化

Xiangyu Zhang ,Trent D Evans ,Sunny Chen ,Ismail Sergin ,Jeremiah Stitham ,Se-Jin Jeong ,Astrid Rodriguez-Velez ,Yu-Sheng Yeh ,Arick Park ,In-Hyuk Jung ,Abhinav Diwan ,Joel D Schilling ,Oren Rom ,Arif Yurdagul ,Slava Epelman ,Jaehyung Cho ,Irfan J Lodhi ,Bettina Mittendorfer ,Babak Razani

Use of acidic nanoparticles to rescue macrophage lysosomal dysfunction in atherosclerosis

使用酸性纳米粒子挽救动脉粥样硬化中的巨噬细胞溶酶体功能障碍

Xiangyu Zhang, Santosh Kumar Misra, Parikshit Moitra, Xiuli Zhang, Se-Jin Jeong, Jeremiah Stitham, Astrid Rodriguez-Velez, Arick Park, Yu-Sheng Yeh, William E Gillanders, Daping Fan, Abhinav Diwan, Jaehyung Cho, Slava Epelman, Irfan J Lodhi, Dipanjan Pan, Babak Razani

Evaluation of mTORC1 signaling in mouse atherosclerotic macrophages by flow cytometry and immunofluorescence

利用流式细胞术和免疫荧光法评估小鼠动脉粥样硬化巨噬细胞中的mTORC1信号通路

Xiangyu Zhang ,Jeremiah Stitham ,Astrid Rodriguez-Velez ,Se-Jin Jeong ,Arick Park ,Yu-Sheng Yeh ,Divya Kapoor ,Bettina Mittendorfer ,Babak Razani

Trehalose causes low-grade lysosomal stress to activate TFEB and the autophagy-lysosome biogenesis response

海藻糖引起低度溶酶体应激,从而激活TFEB和自噬-溶酶体生物合成反应。

Se-Jin Jeong ,Jeremiah Stitham ,Trent D Evans ,Xiangyu Zhang ,Astrid Rodriguez-Velez ,Yu-Sheng Yeh ,Joan Tao ,Koki Takabatake ,Slava Epelman ,Irfan J Lodhi ,Joel D Schilling ,Brian J DeBosch ,Abhinav Diwan ,Babak Razani

Inflammasomes: a preclinical assessment of targeting in atherosclerosis

炎症小体:动脉粥样硬化靶向治疗的临床前评估

Stitham, Jeremiah; Rodriguez-Velez, Astrid; Zhang, Xiangyu; Jeong, Se-Jin; Razani, Babak

Surveillance for second breast cancer events in women with a personal history of breast cancer using breast MRI: a systematic review and meta-analysis

利用乳腺MRI监测有乳腺癌病史女性的第二次乳腺癌事件:系统评价和荟萃分析

Haas, Cameron B; Nekhlyudov, Larissa; Lee, Janie M; Javid, Sara H; Bush, Mary; Johnson, Dianne; Gleason, Timothy; Kaufman, Cary; Specht, Jennifer; Stitham, Sean; Wernli, Karen J

Inducing mitophagy in diabetic platelets protects against severe oxidative stress

诱导糖尿病血小板线粒体自噬可抵抗严重的氧化应激

Lee, Seung Hee; Du, Jing; Stitham, Jeremiah; Atteya, Gourg; Lee, Suho; Xiang, Yaozu; Wang, Dandan; Jin, Yu; Leslie, Kristen L; Spollett, Geralyn; Srivastava, Anup; Mannam, Praveen; Ostriker, Allison; Martin, Kathleen A; Tang, Wai Ho; Hwa, John

Aldose reductase-mediated phosphorylation of p53 leads to mitochondrial dysfunction and damage in diabetic platelets

醛糖还原酶介导的 p53 磷酸化导致糖尿病血小板线粒体功能障碍和损伤

Wai Ho Tang, Jeremiah Stitham, Yu Jin, Renjing Liu, Seung Hee Lee, Jing Du, Gourg Atteya, Scott Gleim, Geralyn Spollett, Kathleen Martin, John Hwa

Individual variation of human S1P₁ coding sequence leads to heterogeneity in receptor function and drug interactions

人类S1P₁编码序列的个体差异导致受体功能和药物相互作用的异质性

Hideru Obinata, Sarah Gutkind, Jeremiah Stitham, Toshiaki Okuno, Takehiko Yokomizo, John Hwa, Timothy Hla