Sodium-glucose Co-transporter 2 (SGLT2) inhibitor dapagliflozin acutely activates cardiomyocyte HIF-1α signaling via succinate, a signaling metabolite
钠-葡萄糖协同转运蛋白2 (SGLT2) 抑制剂达格列净通过琥珀酸（一种信号代谢物）急性激活心肌细胞HIF-1α信号通路。
期刊:Journal of Pharmacological Sciences
影响因子:2.9
doi:10.1016/j.jphs.2026.01.008
Sato, Tatsuyuki; Isagawa, Takayuki; Sugiura, Yuki; Sawaki, Daigo; Nakagama, Yu; Kuchimaru, Takahiro; Minatsuki, Shun; Sato, Shigeru; Ono, Kazutoshi; Chuluun-Erdene, Ariunbold; Semba, Hiroaki; Ito, Masamichi; Kawakami, Toshinaru; Tanaka, Ryohei; Sakamoto, Masaya; Asagiri, Masataka; Harada, Hiroshi; Stockmann, Christian; Yonezawa, Tomo; Hirota, Yasushi; Kido, Yasutoshi; Otsu, Kinya; Kohro, Takahide; Manabe, Ichiro; Komuro, Issei; Takeda, Norihiko
