日期 影响因子
日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:
–

An siRNA targeting S6k1 identifies photoreceptor phospholipid metabolism as a contributor to lipid buildup in age-related macular degeneration.

针对 S6k1 的 siRNA 发现光感受器磷脂代谢是导致年龄相关性黄斑变性中脂质积累的因素之一。

期刊:Molecular Therapy-Nucleic Acids
影响因子:6.1
doi:10.1016/j.omtn.2026.102878
Cheng Shun-Yun, Giguere Delaney, Kim San, Seddon Johanna M, Caiazzi Jillian, Gross Katherine, McHugh Nicholas, Echeverria Dimas, Alterman Julia F, Gray-Edwards Heather, Benatti Hector Ribeiro, Renner Lauren, Woolard Hannah, Stoddard Jonathan, McGill Trevor J, Neuringer Martha, Brush Richard S, Agbaga Martin-Paul, Khvorova Anastasia, Punzo Claudio
代谢
S6k
脂代谢
发表日期：2026
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Allogeneic RPE cell suspension manufactured at scale demonstrating preclinical safety and efficacy led to IND approval.

大规模生产的同种异体 RPE 细胞悬液证明了其临床前安全性和有效性，从而获得了 IND 批准

期刊:npj Regenerative Medicine
影响因子:6.5
doi:10.1038/s41536-025-00407-0
Soundararajan Lalitha, Surendran Harshini, Patlolla Niharika, Battu Rajani, Stoddard Jonathan, Arrizabalaga Sebastian, Liu Zengping, Lingam Gopal, Su Xinyi, Ryals Renee C, Pal Rajarshi
细胞生物学
发表日期：2025
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Preformed Vesicle Approach to LNP Manufacturing Enhances Retinal mRNA Delivery.

预成型囊泡法制备LNP可增强视网膜mRNA递送

期刊:Small
影响因子:12.1
doi:10.1002/smll.202400815
Eygeris Yulia, Henderson Michael I, Curtis Allison G, Jozić Antony, Stoddard Jonathan, Reynaga Rene, Chirco Kathleen R, Su Grace Li-Na, Neuringer Martha, Lauer Andreas K, Ryals Renee C, Sahay Gaurav
其它
囊泡
发表日期：2024
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Thiophene-based lipids for mRNA delivery to pulmonary and retinal tissues

基于噻吩的脂质体用于将mRNA递送至肺部和视网膜组织

期刊:Proceedings of the National Academy of Sciences of the United States of America
影响因子:9.1
doi:10.1073/pnas.2307813120
Eygeris, Yulia; Gupta, Mohit; Kim, Jeonghwan; Jozic, Antony; Gautam, Milan; Renner, Jonas; Nelson, Dylan; Bloom, Elissa; Tuttle, Adam; Stoddard, Jonathan; Reynaga, Rene; Neuringer, Martha; Lauer, Andreas K; Ryals, Renee C; Sahay, Gaurav
发表日期：2024
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Development of a translatable gene augmentation therapy for CNGB1-retinitis pigmentosa

开发一种可转化的基因增强疗法用于治疗 CNGB1 基因突变引起的视网膜色素变性

期刊:Molecular Therapy
影响因子:12
doi:10.1016/j.ymthe.2023.04.005
Occelli, Laurence M; Zobel, Lena; Stoddard, Jonathan; Wagner, Johanna; Pasmanter, Nathaniel; Querubin, Janice; Renner, Lauren M; Reynaga, Rene; Winkler, Paige A; Sun, Kelian; Marinho, Luis Felipe L P; O'Riordan, Catherine R; Frederick, Amy; Lauer, Andreas; Tsang, Stephen H; Hauswirth, William W; McGill, Trevor J; Neuringer, Martha; Michalakis, Stylianos; Petersen-Jones, Simon M
CNGB1
发表日期：2023
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Increasing the Efficacy of Gold Nanorod Uptake in Stem Cell-Derived Therapeutic Cells: Implications for Stem Cell Labeling and Optical Coherence Tomography Imaging

提高干细胞衍生治疗细胞对金纳米棒的摄取效率：对干细胞标记和光学相干断层扫描成像的启示

期刊:ACS Applied Nano Materials
影响因子:5.5
doi:10.1021/acsanm.2c00958
Marquart, Grant W; Stoddard, Jonathan; Kinnison, Karen; Zhou, Felicia; Hugo, Richard; Ryals, Renee; Shubert, Scott; McGill, Trevor J; Mackiewicz, Marilyn R
细胞生物学
发育与干细胞
干细胞
发表日期：2022
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Transplantation of retinal pigment epithelium and photoreceptors generated concomitantly via small molecule-mediated differentiation rescues visual function in rodent models of retinal degeneration

通过小分子介导的分化作用同时生成视网膜色素上皮和感光细胞，并将这些细胞移植到视网膜变性啮齿动物模型中，可以挽救其视觉功能。

期刊:Stem Cell Research & Therapy
影响因子:7.3
doi:10.1186/s13287-021-02134-x
Surendran, Harshini; Nandakumar, Swapna; Reddy K, Vijay Bhaskar; Stoddard, Jonathan; Mohan K, Varsha; Upadhyay, Pramod K; McGill, Trevor J; Pal, Rajarshi
细胞生物学
发表日期：2021
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Clinical-grade stem cell-derived retinal pigment epithelium patch rescues retinal degeneration in rodents and pigs

临床级干细胞衍生视网膜色素上皮贴片可挽救啮齿动物和猪的视网膜退化

期刊:Science Translational Medicine
影响因子:14.6
doi:10.1126/scitranslmed.aat5580
Sharma, Ruchi; Khristov, Vladimir; Rising, Aaron; Jha, Balendu Shekhar; Dejene, Roba; Hotaling, Nathan; Li, Yichao; Stoddard, Jonathan; Stankewicz, Casey; Wan, Qin; Zhang, Connie; Campos, Mercedes Maria; Miyagishima, Kiyoharu J; McGaughey, David; Villasmil, Rafael; Mattapallil, Mary; Stanzel, Boris; Qian, Haohua; Wong, Wai; Chase, Lucas; Charles, Steve; McGill, Trevor; Miller, Sheldon; Maminishkis, Arvydas; Amaral, Juan; Bharti, Kapil
细胞生物学
发育与干细胞
干细胞
发表日期：2019
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Bardet-Biedl Syndrome in rhesus macaques: A nonhuman primate model of retinitis pigmentosa.

恒河猴的巴德-比德尔综合征：视网膜色素变性的非人灵长类动物模型

期刊:Experimental Eye Research
影响因子:2.7
doi:10.1016/j.exer.2019.107825
Peterson Samuel M, McGill Trevor J, Puthussery Teresa, Stoddard Jonathan, Renner Lauren, Lewis Anne D, Colgin Lois M A, Gayet Jacqueline, Wang Xiaojie, Prongay Kamm, Cullin Cassandra, Dozier Brandy L, Ferguson Betsy, Neuringer Martha
Human
Primate
Rhesus
发表日期：2019
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Subretinal Transplantation of Human Central Nervous System Stem Cells Stimulates Controlled Proliferation of Endogenous Retinal Pigment Epithelium

人中枢神经系统干细胞视网膜下移植可刺激内源性视网膜色素上皮细胞的受控增殖

期刊:Translational Vision Science & Technology
影响因子:2.6
doi:10.1167/tvst.8.3.43
McGill, Trevor J; Osborne, Linda; Lu, Bin; Stoddard, Jonathan; Huhn, Stephen; Tsukamoto, Ann; Capela, Alexandra
发育与干细胞
上皮细胞
神经科学
Human
干细胞
细胞生物学
发表日期：2019
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