日期 影响因子
日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:
–

Obicetrapib and ezetimibe enhance LDL receptor-mediated VLDL clearance and regress atherosclerosis on atorvastatin background

奥比塞曲匹和依折麦布可增强低密度脂蛋白受体介导的极低密度脂蛋白清除，并在阿托伐他汀背景下逆转动脉粥样硬化

期刊:Journal of Lipid Research
影响因子:4.1
doi:10.1016/j.jlr.2026.101028
Inia, José A; Zhang, Leo H; Keijzer, Nanda; Worms, Nicole; van Nieuwkoop-van Straalen, Anita; Ditmarsch, Marc; de Kleer, Mathijs; Jukema, J Wouter; Kastelein, John J P; Szarek, Michael; van den Hoek, Anita M; Stokman, Geurt; Pieterman, Elsbet J; Princen, Hans M G
信号转导
心血管
动脉粥样硬化
发表日期：2026
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Erratum: Proof-of-concept study for liver-directed miQURE technology in a dyslipidemic mouse model

更正：在血脂异常小鼠模型中开展肝脏靶向 miQURE 技术概念验证研究

期刊:Molecular Therapy-Nucleic Acids
影响因子:6.1
doi:10.1016/j.omtn.2024.102189
Zancanella, Vanessa; Vallès, Astrid; Liefhebber, Jolanda M P; Paerels, Lieke; Tornero, Carlos Vendrell; Wattimury, Hendrina; van der Zon, Tom; van Rooijen, Kristel; Golinska, Monika; Grevelink, Tamar; Ehlert, Erich; Pieterman, Elsbet Jantine; Keijzer, Nanda; Gerardus Princen, Hans Marinus; Stokman, Geurt; Liu, Ying Poi
心血管
发表日期：2024
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Semaglutide Has Beneficial Effects on Non-Alcoholic Steatohepatitis in Ldlr-/-.Leiden Mice

司美格鲁肽对 Ldlr-/-.Leiden 小鼠的非酒精性脂肪性肝炎具有有益作用

期刊:International Journal of Molecular Sciences
影响因子:4.9
doi:10.3390/ijms24108494
Inia, José A; Stokman, Geurt; Morrison, Martine C; Worms, Nicole; Verschuren, Lars; Caspers, Martien P M; Menke, Aswin L; Petitjean, Louis; Chen, Li; Petitjean, Mathieu; Jukema, J Wouter; Princen, Hans M G; van den Hoek, Anita M
肝炎
发表日期：2023
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A Novel, Orally Bioavailable, Small-Molecule Inhibitor of PCSK9 With Significant Cholesterol-Lowering Properties In Vivo.

一种新型的、口服生物利用度高的PCSK9小分子抑制剂，具有显著的体内降胆固醇特性

期刊:Journal of Lipid Research
影响因子:4.1
doi:10.1016/j.jlr.2022.100293
Suchowerska Alexandra K, Stokman Geurt, Palmer James T, Coghlan Phillip A, Pieterman Elsbet J, Keijzer Nanda, Lambert Gilles, Chemello Kevin, Jaafar Ali K, Parmar Jasneet, Yan Liping, Tong Yingtao, Mu Lin, Princen Hans M G, Bonnar James, Evison Benny J
信号转导
发表日期：2022
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Dual targeting of hepatic fibrosis and atherogenesis by icosabutate, an engineered eicosapentaenoic acid derivative

二十碳五烯酸衍生物二十碳丁酸酯可双重靶向肝纤维化和动脉粥样硬化。

期刊:Liver International
影响因子:5.2
doi:10.1111/liv.14643
Stokman, Geurt; van den Hoek, Anita M; Denker Thorbekk, Ditte; Pieterman, Elsbet J; Skovgård Veidal, Sanne; Basta, Brittany; Iruarrizaga-Lejarreta, Marta; van der Hoorn, José W; Verschuren, Lars; Berbée, Jimmy F P; Rensen, Patrick C N; Skjaeret, Tore; Alonso, Cristina; Feigh, Michael; Kastelein, John J P; Friedman, Scott L; Princen, Hans M G; Fraser, David A
心血管
动脉粥样硬化
发表日期：2020
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Epac-Rap signaling reduces oxidative stress in the tubular epithelium

Epac-Rap信号通路可降低肾小管上皮细胞的氧化应激。

期刊:Journal of the American Society of Nephrology
影响因子:9.4
doi:10.1681/ASN.2013070679
Stokman, Geurt; Qin, Yu; Booij, Tijmen H; Ramaiahgari, Sreenivasa; Lacombe, Marie; Dolman, M Emmy M; van Dorenmalen, Kim M A; Teske, Gwendoline J D; Florquin, Sandrine; Schwede, Frank; van de Water, Bob; Kok, Robbert J; Price, Leo S
氧化应激
上皮细胞
信号转导
细胞生物学
毒理研究
发表日期：2014
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cAMP signalling protects proximal tubular epithelial cells from cisplatin-induced apoptosis via activation of Epac.

cAMP信号通过激活Epac来保护近端肾小管上皮细胞免受顺铂诱导的细胞凋亡

期刊:British Journal of Pharmacology
影响因子:7.7
doi:10.1111/j.1476-5381.2011.01594.x
Qin Yu, Stokman Geurt, Yan Kuan, Ramaiahgari Sreenivasa, Verbeek Fons, de Graauw Marjo, van de Water Bob, Price Leo S
信号转导
细胞生物学
Apoptosis
凋亡
发表日期：2012
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Epac-Rap signaling reduces cellular stress and ischemia-induced kidney failure

Epac-Rap信号通路可减轻细胞应激和缺血引起的肾衰竭

期刊:Journal of the American Society of Nephrology
影响因子:9.4
doi:10.1681/ASN.2010040423
Stokman, Geurt; Qin, Yu; Genieser, Hans-Gottfried; Schwede, Frank; de Heer, Emile; Bos, Johannes L; Bajema, Ingeborg M; van de Water, Bob; Price, Leo S
信号转导
细胞生物学
发表日期：2011
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Focal adhesion kinase signaling mediates acute renal injury induced by ischemia/reperfusion

局灶性黏着斑激酶信号通路介导缺血/再灌注引起的急性肾损伤。

期刊:American Journal of Pathology
影响因子:3.6
doi:10.1016/j.ajpath.2011.08.025
Qin, Yu; Alderliesten, Maaike C; Stokman, Geurt; Pennekamp, Petra; Bonventre, Joseph V; de Heer, Emile; Ichimura, Takaharu; de Graauw, Marjo; Price, Leo S; van de Water, Bob
信号转导
毒理研究
肾损伤
发表日期：2011
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Chemokine expression in renal ischemia/reperfusion injury is most profound during the reparative phase.

肾脏缺血/再灌注损伤中趋化因子的表达在修复期最为显著

期刊:International Immunology
影响因子:3.2
doi:10.1093/intimm/dxq025
Stroo Ingrid, Stokman Geurt, Teske Gwen J D, Raven Anje, Butter Loes M, Florquin Sandrine, Leemans Jaklien C
毒理研究
发表日期：2010
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