Characterization of TNG348: A Selective, Allosteric USP1 Inhibitor That Synergizes with PARP Inhibitors in Tumors with Homologous Recombination Deficiency.
TNG348 的特性：一种选择性变构 USP1 抑制剂，可与 PARP 抑制剂在同源重组缺陷肿瘤中发挥协同作用
期刊:Molecular Cancer Therapeutics
影响因子:5.5
doi:10.1158/1535-7163.MCT-24-0515
Simoneau Antoine, Pratt Charlotte B, Wu Hsin-Jung, Rajeswaran Shreya S, Comer Charlotte Grace, Sudsakorn Sirimas, Zhang Wenhai, Liu Shangtao, Meier Samuel R, Choi Ashley H, Khendu Tenzing, Stowe Hannah, Shen Binzhang, Whittington Douglas A, Chen Yingnan, Yu Yi, Mallender William D, Feng Tianshu, Andersen Jannik N, Maxwell John P, Throner Scott
