日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Discovery of Small-Molecule Antagonists of PHF1 and 19 Demonstrates the Ligandability of PRC2 Accessory Proteins

PHF1和PHF19小分子拮抗剂的发现证明了PRC2辅助蛋白的配体结合能力

Amick, Isabelle E; Johnson, Rebecca L; Liu, Jiuyang; Bussey-Sutton, Cameron R; Mancera-Ortiz, Ikeer Y; Norris-Drouin, Jacqueline L; Boyd, Shelton R; Cholensky, Stephanie H; Spangler, Cathy J; McGinty, Robert K; Strahl, Brian D; Kutateladze, Tatiana G; Frye, Stephen V; James, Lindsey I

A submission checklist to improve transparency and replicability of functional genomics data analyses

提交清单旨在提高功能基因组学数据分析的透明度和可重复性

Hepperla, Austin J; Hardison, Ross C; Colbran, Roger J; Strahl, Brian D; Simon, Jeremy M

HMGN1 and HMGN2 are recruited to acetylated and histone variant H2A.Z-containing nucleosomes to regulate chromatin state and transcription.

HMGN1 和 HMGN2 被募集到乙酰化和含有组蛋白变体 H2A.Z 的核小体上,以调节染色质状态和转录。

Gohil Riya, Gao Zhihan, Lewis Rebecca A, Burkholder Nathaniel T, Strahl Brian D, Dowen Jill M

Rapid CRISPR-Cas9 Genome Editing in S. cerevisiae

在酿酒酵母中进行快速 CRISPR-Cas9 基因组编辑

Rostamian, Hosein; Madden, Ethan W; Kaplan, Frank M; Kim, Riley; Isom, Daniel G; Strahl, Brian D

A SETD2-CDK1-lamin axis maintains nuclear morphology and genome stability.

SETD2-CDK1-核纤层蛋白轴维持细胞核形态和基因组稳定性。

Khan Abid, Zhang Cheng, Nguyen Phu G, Metts James M, Collins Lucas C, Jain Kanishk, Mills C Allie, Vlach Logan, Li Kelin, Brademeyer Amanda L, Bowman Brittany M, Major Michael B, Aubé Jeffrey, Herring Laura E, Rathmell W Kimryn, Mason Frank M, Davis Ian J, Zhang Qing, Strahl Brian D

A needed nomenclature for nucleosomes

核小体命名法的必要性

Keogh, Michael-Christopher; Almouzni, Genevieve; Andrews, Andrew J; Armache, Karim-Jean; Arrowsmith, Cheryl H; Baek, Sung Hee; Bedford, Mark T; Bernstein, Emily; Côté, Jacques; David, Yael; Denu, John M; Fierz, Beat; Garcia, Benjamin A; Glass, Karen C; Gozani, Or; Helin, Kristian; Henikoff, Steven; Jensen, Ole N; Josefowicz, Steven Z; Kelleher, Neil L; Kutateladze, Tatiana G; Lindner, Herbert H; Lu, Chao; Luger, Karolin; Mallick, Parag; Musselman, Catherine A; Muir, Tom W; Paša-Tolić, Ljiljana; Schneider, Robert; Shi, Xiaobing; Shi, Yang; Sidoli, Simone; Smith, Lloyd M; Tyler, Jessica K; Wolberger, Cynthia; Workman, Jerry L; Strahl, Brian D; Young, Nicolas L

Multivalent binding of the tardigrade Dsup protein to chromatin promotes yeast survival and longevity upon exposure to oxidative damage

水熊虫Dsup蛋白与染色质的多价结合促进酵母在暴露于氧化损伤后存活和延长寿命。

Aguilar, Rhiannon R; Khan, Laiba F; Cummins, Christopher K; Arslanovic, Nina; Grauer, Thea; Birmingham, Kaylah; Kasliwal, Kritika; Posnikoff, Spike D L; Chakraborty, Ujani; Hickman, Allison R; Watson, Rachel; Ezell, Ryan J; Hunt, Sabrina R; Mukhsinova, Laylo; Willis, Hannah E; Cowles, Martis W; Garner, Richard; Shim, Abraham; Gutierrez, J Ignacio; Venters, Bryan J; Marunde, Matthew R; Strahl, Brian D; Keogh, Michael-Christopher; Tyler, Jessica K

Histone H3 N-terminal recognition by the PHD finger of PHRF1 is required for proper DNA damage response

PHRF1的PHD指结构域识别组蛋白H3 N端是DNA损伤反应所必需的。

Jain, Kanishk; Kougnassoukou Tchara, Pata-Eting; Khan, Abid; Mengistalem, Amanuel B; Holland, Aidan P; Bowman, Christopher N; Marunde, Matthew R; Engel, Tiffany A; Popova, Irina K; Cooke, Spencer W; Krajewski, Krzysztof; Keogh, Michael-Christopher; Lambert, Jean-Philippe; Strahl, Brian D

SETD2 suppresses tumorigenesis in a KRAS(G12C)-driven lung cancer model, and its catalytic activity is regulated by histone acetylation.

SETD2 在 KRAS(G12C) 驱动的肺癌模型中抑制肿瘤发生,其催化活性受组蛋白乙酰化的调控

Mack Ricardo J, Flores Natasha M, Fox Geoffrey C, Dong Hanyang, Cebeci Metehan, Hausmann Simone, Chasan Tourkian, Dowen Jill M, Strahl Brian D, Mazur Pawel K, Gozani Or

Spt6-Spn1 interaction is required for RNA polymerase II association and precise nucleosome positioning along transcribed genes

Spt6-Spn1相互作用是RNA聚合酶II结合以及核小体沿转录基因精确定位所必需的。

Chen, Boning; Dronamraju, Raghuvar; Smith-Kinnaman, Whitney R; Peck Justice, Sarah A; Hepperla, Austin J; MacAlpine, Heather K; Simon, Jeremy M; Mosley, Amber L; MacAlpine, David M; Strahl, Brian D