日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

A novel class of sulphonamides potently block malaria transmission by targeting a Plasmodium vacuole membrane protein

一类新型磺胺类药物通过靶向疟原虫液泡膜蛋白有效阻断疟疾传播

Sabrina Yahiya, Charlie N Saunders, Sarah Hassan, Ursula Straschil, Oliver J Fischer, Ainoa Rueda-Zubiaurre, Silvia Haase, Gema Vizcay-Barrena, Mufuliat Toyin Famodimu, Sarah Jordan, Michael J Delves, Edward W Tate, Anna Barnard, Matthew J Fuchter, Jake Baum

The Novel bis-1,2,4-Triazine MIPS-0004373 Demonstrates Rapid and Potent Activity against All Blood Stages of the Malaria Parasite

新型双-1,2,4-三嗪化合物MIPS-0004373对疟原虫所有血液阶段均表现出快速而强效的活性

Ellis, Katherine M; Lucantoni, Leonardo; Chavchich, Marina; Abraham, Matthew; De Paoli, Amanda; Luth, Madeline R; Zeeman, Anne-Marie; Delves, Michael J; Terán, Fernando Sánchez-Román; Straschil, Ursula; Baum, Jake; Kocken, Clemens H M; Ralph, Stuart A; Winzeler, Elizabeth A; Avery, Vicky M; Edstein, Michael D; Baell, Jonathan B; Creek, Darren J

Screen of traditional soup broths with reported antipyretic activity towards the discovery of potential antimalarials

筛选具有退热活性的传统汤料,以发现潜在的抗疟药物

Straschil, Ursula; Witmer, Kathrin; Delves, Michael J; Marks, Stephen D; Baum, Jake

A high throughput screen for next-generation leads targeting malaria parasite transmission

针对疟原虫传播的下一代线索的高通量筛选

Michael J Delves, Celia Miguel-Blanco, Holly Matthews, Irene Molina, Andrea Ruecker, Sabrina Yahiya, Ursula Straschil, Matthew Abraham, María Luisa León, Oliver J Fischer, Ainoa Rueda-Zubiaurre, Jochen R Brandt, Álvaro Cortés, Anna Barnard, Matthew J Fuchter, Félix Calderón, Elizabeth A Winzeler, Ro

An inexpensive open source 3D-printed membrane feeder for human malaria transmission studies

一种用于人类疟疾传播研究的低成本开源3D打印膜式喂食器

Witmer, Kathrin; Sherrard-Smith, Ellie; Straschil, Ursula; Tunnicliff, Mark; Baum, Jake; Delves, Michael

Extinctions, genetic erosion and conservation options for the black rhinoceros (Diceros bicornis)

黑犀牛(Diceros bicornis)的灭绝、基因侵蚀和保护方案

Moodley, Yoshan; Russo, Isa-Rita M; Dalton, Desiré L; Kotzé, Antoinette; Muya, Shadrack; Haubensak, Patricia; Bálint, Boglárka; Munimanda, Gopi K; Deimel, Caroline; Setzer, Andrea; Dicks, Kara; Herzig-Straschil, Barbara; Kalthoff, Daniela C; Siegismund, Hans R; Robovský, Jan; O'Donoghue, Paul; Bruford, Michael W

Plasmodium Merozoite TRAP Family Protein Is Essential for Vacuole Membrane Disruption and Gamete Egress from Erythrocytes

疟原虫裂殖子TRAP家族蛋白对于红细胞液泡膜的破坏和配子逸出至关重要

Bargieri, Daniel Y; Thiberge, Sabine; Tay, Chwen L; Carey, Alison F; Rantz, Alice; Hischen, Florian; Lorthiois, Audrey; Straschil, Ursula; Singh, Pallavi; Singh, Shailja; Triglia, Tony; Tsuboi, Takafumi; Cowman, Alan; Chitnis, Chetan; Alano, Pietro; Baum, Jake; Pradel, Gabriele; Lavazec, Catherine; Ménard, Robert

Genome-wide functional analysis of Plasmodium protein phosphatases reveals key regulators of parasite development and differentiation

对疟原虫蛋白磷酸酶的全基因组功能分析揭示了寄生虫发育和分化的关键调控因子

Guttery, David S; Poulin, Benoit; Ramaprasad, Abhinay; Wall, Richard J; Ferguson, David J P; Brady, Declan; Patzewitz, Eva-Maria; Whipple, Sarah; Straschil, Ursula; Wright, Megan H; Mohamed, Alyaa M A H; Radhakrishnan, Anand; Arold, Stefan T; Tate, Edward W; Holder, Anthony A; Wickstead, Bill; Pain, Arnab; Tewari, Rita

A male and female gametocyte functional viability assay to identify biologically relevant malaria transmission-blocking drugs

通过雄性和雌性配子体功能活力测定来鉴定生物学相关的疟疾传播阻断药物

A Ruecker, D K Mathias, U Straschil, T S Churcher, R R Dinglasan, D Leroy, R E Sinden, M J Delves

Changes in metabolic phenotypes of Plasmodium falciparum in vitro cultures during gametocyte development

恶性疟原虫配子体发育过程中体外培养代谢表型的变化

Lamour, Sabrina D; Straschil, Ursula; Saric, Jasmina; Delves, Michael J