日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Liver-innervating vagal sensory neurons are indispensable for the development of hepatic steatosis and anxiety-like behavior in diet-induced obese mice

支配肝脏的迷走神经感觉神经元对于饮食诱导肥胖小鼠肝脂肪变性和焦虑样行为的发生发展至关重要。

Jiyeon Hwang ,Sangbhin Lee ,Junichi Okada ,Li Liu ,Jeffrey E Pessin ,Streamson C Chua Jr ,Gary J Schwartz ,Young-Hwan Jo

The gut signals to AGRP-expressing cells of the pituitary to control glucose homeostasis

肠道向垂体中表达AGRP的细胞发出信号,以控制葡萄糖稳态。

Shun-Mei Liu ,Bruno Ifebi ,Fred Johnson ,Alison Xu ,Jacquelin Ho ,Yunlei Yang ,Gary Schwartz ,Young Hwan Jo ,Streamson Chua Jr

Conversion of the death inhibitor ARC to a killer activates pancreatic β cell death in diabetes

死亡抑制剂 ARC 转化为杀伤剂可激活糖尿病患者的胰腺 β 细胞死亡

Wendy M McKimpson, Yun Chen, James A Irving, Min Zheng, Jeremy Weinberger, Wilson Lek Wen Tan, Zenia Tiang, Alistair M Jagger, Streamson C Chua Jr, Jeffrey E Pessin, Roger S-Y Foo, David A Lomas, Richard N Kitsis

Cyclin-dependent kinase 4/6 inhibitors require an arcuate-to-paraventricular hypothalamus melanocortin circuit to treat diet-induced obesity

细胞周期蛋白依赖性激酶4/6抑制剂需要弓状核-室旁核-下丘脑黑皮质素环路才能治疗饮食引起的肥胖。

Iqbal, Niloy Jafar; Schwartz, Gary J; Zhao, Hongling; Zhu, Liang; Chua, Streamson , Jr

Optogenetic stimulation of the liver-projecting melanocortinergic pathway promotes hepatic glucose production

光遗传学刺激肝脏投射黑素皮质通路促进肝葡萄糖生成

Eunjin Kwon, Hye-Young Joung, Shun-Mei Liu, Streamson C Chua Jr, Gary J Schwartz, Young-Hwan Jo

Leptin-mediated differential regulation of microsomal triglyceride transfer protein in the intestine and liver affects plasma lipids

瘦素介导的肠道和肝脏微粒体甘油三酯转运蛋白的差异调节影响血浆脂质

Jahangir Iqbal, Eduardo Mascareno, Streamson Chua, M Mahmood Hussain

Activation of temperature-sensitive TRPV1-like receptors in ARC POMC neurons reduces food intake

ARC POMC 神经元中温度敏感的 TRPV1 样受体的激活会减少食物摄入量

Jae Hoon Jeong, Dong Kun Lee, Shun-Mei Liu, Streamson C Chua Jr, Gary J Schwartz, Young-Hwan Jo

A gut-brain axis regulating glucose metabolism mediated by bile acids and competitive fibroblast growth factor actions at the hypothalamus

胆汁酸和下丘脑竞争性成纤维细胞生长因子作用介导的肠脑轴调节葡萄糖代谢

Shunmei Liu, Genevieve Marcelin, Clemence Blouet, Jae Hoon Jeong, Young-Hwan Jo, Gary J Schwartz, Streamson Chua Jr

Cyclin-dependent kinase 4 is a preclinical target for diet-induced obesity

细胞周期蛋白依赖性激酶 4 是饮食引起肥胖的临床前靶点

Niloy Jafar Iqbal, Zhonglei Lu, Shun Mei Liu, Gary J Schwartz, Streamson Chua Jr, Liang Zhu

Cutting Edge: Elevated Leptin during Diet-Induced Obesity Reduces the Efficacy of Tumor Immunotherapy

前沿研究:饮食诱导肥胖期间瘦素水平升高会降低肿瘤免疫疗法的疗效

Murphy, Katherine A; James, Britnie R; Sjaastad, Frances V; Kucaba, Tamara A; Kim, Hyunjoon; Brincks, Erik L; Chua, Streamson C Jr; Wilber, Andrew; Griffith, Thomas S