日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Liver-innervating vagal sensory neurons are indispensable for the development of hepatic steatosis and anxiety-like behavior in diet-induced obese mice

支配肝脏的迷走神经感觉神经元对于饮食诱导肥胖小鼠肝脂肪变性和焦虑样行为的发生发展至关重要。

Jiyeon Hwang ,Sangbhin Lee ,Junichi Okada ,Li Liu ,Jeffrey E Pessin ,Streamson C Chua Jr ,Gary J Schwartz ,Young-Hwan Jo

Conversion of the death inhibitor ARC to a killer activates pancreatic β cell death in diabetes

死亡抑制剂 ARC 转化为杀伤剂可激活糖尿病患者的胰腺 β 细胞死亡

Wendy M McKimpson, Yun Chen, James A Irving, Min Zheng, Jeremy Weinberger, Wilson Lek Wen Tan, Zenia Tiang, Alistair M Jagger, Streamson C Chua Jr, Jeffrey E Pessin, Roger S-Y Foo, David A Lomas, Richard N Kitsis

Optogenetic stimulation of the liver-projecting melanocortinergic pathway promotes hepatic glucose production

光遗传学刺激肝脏投射黑素皮质通路促进肝葡萄糖生成

Eunjin Kwon, Hye-Young Joung, Shun-Mei Liu, Streamson C Chua Jr, Gary J Schwartz, Young-Hwan Jo

Activation of temperature-sensitive TRPV1-like receptors in ARC POMC neurons reduces food intake

ARC POMC 神经元中温度敏感的 TRPV1 样受体的激活会减少食物摄入量

Jae Hoon Jeong, Dong Kun Lee, Shun-Mei Liu, Streamson C Chua Jr, Gary J Schwartz, Young-Hwan Jo

Cutting Edge: Elevated Leptin during Diet-Induced Obesity Reduces the Efficacy of Tumor Immunotherapy

前沿研究:饮食诱导肥胖期间瘦素水平升高会降低肿瘤免疫疗法的疗效

Murphy, Katherine A; James, Britnie R; Sjaastad, Frances V; Kucaba, Tamara A; Kim, Hyunjoon; Brincks, Erik L; Chua, Streamson C Jr; Wilber, Andrew; Griffith, Thomas S

ARC is essential for maintaining pancreatic islet structure and β-cell viability during type 2 diabetes

ARC 对于维持 2 型糖尿病期间的胰岛结构和 β 细胞活力至关重要

Wendy M McKimpson, Min Zheng, Streamson C Chua, Jeffrey E Pessin, Richard N Kitsis2

Loss of the RNA polymerase III repressor MAF1 confers obesity resistance

RNA聚合酶III阻遏物MAF1的缺失赋予了肥胖抵抗力

Nicolas Bonhoure, Ashlee Byrnes, Robyn D Moir, Wassim Hodroj, Frédéric Preitner, Viviane Praz, Genevieve Marcelin, Streamson C Chua Jr, Nuria Martinez-Lopez, Rajat Singh, Norman Moullan, Johan Auwerx, Gilles Willemin, Hardik Shah, Kirsten Hartil, Bhavapriya Vaitheesvaran, Irwin Kurland, Nouria Herna

Role of melanocortin signaling in neuroendocrine and metabolic actions of leptin in male rats with uncontrolled diabetes

黑皮质素信号在未控制糖尿病雄性大鼠的神经内分泌和瘦素代谢作用中的作用

Thomas H Meek, Miles E Matsen, Vincent Damian, Alex Cubelo, Streamson C Chua Jr, Gregory J Morton

The antidepressant trans-2-phenylcyclopropylamine protects mice from high-fat-diet-induced obesity

抗抑郁药反式-2-苯基环丙胺可保护小鼠免受高脂饮食诱导的肥胖症的影响。

Shemesh, Adi; Abdulla, Arian; Yang, Fajun; Chua, Streamson C; Pessin, Jeffrey E; Zong, Haihong

The apoptosis inhibitor ARC alleviates the ER stress response to promote β-cell survival

凋亡抑制剂ARC可减轻内质网应激反应,从而促进β细胞存活。

McKimpson, Wendy M; Weinberger, Jeremy; Czerski, Lech; Zheng, Min; Crow, Michael T; Pessin, Jeffrey E; Chua, Streamson C Jr; Kitsis, Richard N