日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Deficiency of the lipid synthesis enzyme, DGAT1, extends longevity in mice.

脂质合成酶 DGAT1 的缺乏会延长小鼠的寿命

Streeper Ryan S, Grueter Carrie A, Salomonis Nathan, Cases Sylvaine, Levin Malin C, Koliwad Suneil K, Zhou Ping, Hirschey Mattew D, Verdin Eric, Farese Robert V Jr

DGAT enzymes are required for triacylglycerol synthesis and lipid droplets in adipocytes

DGAT酶是脂肪细胞中三酰甘油合成和脂滴形成所必需的。

Harris, Charles A; Haas, Joel T; Streeper, Ryan S; Stone, Scot J; Kumari, Manju; Yang, Kui; Han, Xianlin; Brownell, Nicholas; Gross, Richard W; Zechner, Rudolf; Farese, Robert V Jr

DGAT1-dependent triacylglycerol storage by macrophages protects mice from diet-induced insulin resistance and inflammation

巨噬细胞中DGAT1依赖的三酰甘油储存可保护小鼠免受饮食诱导的胰岛素抵抗和炎症的影响

Koliwad, Suneil K; Streeper, Ryan S; Monetti, Mara; Cornelissen, Ivo; Chan, Liana; Terayama, Koji; Naylor, Stephen; Rao, Meghana; Hubbard, Brian; Farese, Robert V Jr

SIRT4 regulates fatty acid oxidation and mitochondrial gene expression in liver and muscle cells

SIRT4 调控肝脏和肌肉细胞中的脂肪酸氧化和线粒体基因表达。

Nasrin, Nargis; Wu, Xiaoping; Fortier, Eric; Feng, Yajun; Bare', Olivia Claire; Chen, Sumiao; Ren, Xianglin; Wu, Zhidan; Streeper, Ryan S; Bordone, Laura

Mammalian Sir2 homolog SIRT3 regulates global mitochondrial lysine acetylation

哺乳动物Sir2同源物SIRT3调控线粒体整体赖氨酸乙酰化

Lombard, David B; Alt, Frederick W; Cheng, Hwei-Ling; Bunkenborg, Jakob; Streeper, Ryan S; Mostoslavsky, Raul; Kim, Jennifer; Yancopoulos, George; Valenzuela, David; Murphy, Andrew; Yang, Yinhua; Chen, Yaohui; Hirschey, Matthew D; Bronson, Roderick T; Haigis, Marcia; Guarente, Leonard P; Farese, Robert V Jr; Weissman, Sherman; Verdin, Eric; Schwer, Bjoern

Myostatin modulates adipogenesis to generate adipocytes with favorable metabolic effects

肌肉生长抑制素调节脂肪生成,从而产生具有有利代谢效应的脂肪细胞。

Feldman, Brian J; Streeper, Ryan S; Farese, Robert V Jr; Yamamoto, Keith R