日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

A miniaturized mode-of-action profiling platform enables high throughput characterization of the molecular and cellular dynamics of EZH2 inhibition

微型作用模式分析平台能够高通量表征 EZH2 抑制的分子和细胞动力学

Lilia Falkenstern #, Victoria Georgi #, Stefanie Bunse, Volker Badock, Manfred Husemann, Ulrike Roehn, Timo Stellfeld, Mark Fitzgerald, Steven Ferrara, Detlef Stöckigt, Carlo Stresemann, Ingo V Hartung, Amaury Fernández-Montalván

Implementing machine learning techniques for continuous emotion prediction from uniformly segmented voice recordings

利用机器学习技术从均匀分割的语音记录中进行连续情感预测

Diemerling, Hannes; Stresemann, Leonie; Braun, Tina; von Oertzen, Timo

Boosting corrects a memory B cell defect in SARS-CoV-2 mRNA-vaccinated patients with inflammatory bowel disease

加强免疫可纠正接种过SARS-CoV-2 mRNA疫苗的炎症性肠病患者的记忆B细胞缺陷

Kathryn A Pape ,Thamotharampillai Dileepan ,William E Matchett ,Charles Ellwood ,Samuel Stresemann ,Amanda J Kabage ,Daria Kozysa ,Clayton Evert ,Michael Matson ,Sharon Lopez ,Peter D Krueger ,Carolyn T Graiziger ,Byron P Vaughn ,Eugenia Shmidt ,Joshua Rhein ,Timothy W Schacker ,Tyler D Bold ,Ryan A Langlois ,Alexander Khoruts ,Marc K Jenkins

Identification of Small Molecules that Modulate Mutant p53 Condensation

鉴定调节突变型p53凝聚的小分子

Lemos, Clara; Schulze, Luise; Weiske, Joerg; Meyer, Hanna; Braeuer, Nico; Barak, Naomi; Eberspächer, Uwe; Werbeck, Nicolas; Stresemann, Carlo; Lange, Martin; Lesche, Ralf; Zablowsky, Nina; Juenemann, Katrin; Kamburov, Atanas; Luh, Laura Martina; Leissing, Thomas Markus; Mortier, Jeremie; Steckel, Michael; Steuber, Holger; Eis, Knut; Eheim, Ashley; Steigemann, Patrick

Functional diversity of inhibitors tackling the differentiation blockage of MLL-rearranged leukemia

针对MLL重排白血病分化阻滞的抑制剂的功能多样性

Krzysztof Brzezinka ,Ekaterina Nevedomskaya ,Ralf Lesche ,Michael Steckel ,Ashley L Eheim ,Andrea Haegebarth ,Carlo Stresemann

Isolation of circulating tumor cells from pancreatic cancer by automated filtration

利用自动化过滤法分离胰腺癌循环肿瘤细胞

Brychta, Nora; Drosch, Michael; Driemel, Christiane; Fischer, Johannes C; Neves, Rui P; Esposito, Irene; Knoefel, Wolfram; Möhlendick, Birte; Hille, Claudia; Stresemann, Antje; Krahn, Thomas; Kassack, Matthias U; Stoecklein, Nikolas H; von Ahsen, Oliver

EZH2 Inhibition Blocks Multiple Myeloma Cell Growth through Upregulation of Epithelial Tumor Suppressor Genes

EZH2 抑制剂通过上调上皮肿瘤抑制基因来阻断多发性骨髓瘤细胞生长

Henar Hernando, Kathy A Gelato, Ralf Lesche, Georg Beckmann, Silke Koehr, Saskia Otto, Patrick Steigemann, Carlo Stresemann

Coordination of stress signals by the lysine methyltransferase SMYD2 promotes pancreatic cancer

赖氨酸甲基转移酶 SMYD2 协调应激信号促进胰腺癌

Nicolas Reynoird, Pawel K Mazur, Timo Stellfeld, Natasha M Flores, Shane M Lofgren, Scott M Carlson, Elisabeth Brambilla, Pierre Hainaut, Ewa B Kaznowska, Cheryl H Arrowsmith, Purvesh Khatri, Carlo Stresemann, Or Gozani, Julien Sage

Quantification of histone H3 Lys27 trimethylation (H3K27me3) by high-throughput microscopy enables cellular large-scale screening for small-molecule EZH2 inhibitors

通过高通量显微镜对组蛋白 H3 Lys27 三甲基化 (H3K27me3) 进行量化,可以实现细胞大规模筛选小分子 EZH2 抑制剂

Svenja Luense, Philip Denner, Amaury Fernández-Montalván, Ingo Hartung, Manfred Husemann, Carlo Stresemann, Stefan Prechtl

Antiproliferative effects of DNA methyltransferase 3B depletion are not associated with DNA demethylation

DNA 甲基转移酶 3B 耗竭的抗增殖作用与 DNA 去甲基化无关

Sabine Hagemann, Dirk Kuck, Carlo Stresemann, Florian Prinz, Bodo Brueckner, Cora Mund, Dominik Mumberg, Anette Sommer