Streuer相关文献与解析，生知库 | 链接生命科学的每一步

Silva-Bermudez, Lina Susana; Streuer, Alexander; Christodoulou, Foteini; Eisele, Philipp; Steiner, Laurenz; Metzgeroth, Georgia; Platten, Michael; Hofmann, Wolf-Karsten; Abba, Mohammed L

白血病

神经科学

FLT3

发表日期：2026

文献求助收藏

The bispecific innate cell engager AFM28 eliminates CD123+ leukemic stem and progenitor cells in AML and MDS

双特异性固有免疫细胞衔接器AFM28可清除急性髓系白血病（AML）和骨髓增生异常综合征（MDS）中的CD123+白血病干细胞和祖细胞。

期刊:Nature Communications

影响因子:14.7

doi:10.1038/s41467-025-63069-y

Nanni Schmitt # ，Jana-Julia Siegler # ，Alexandra Beck ，Thomas Müller ，Izabela Kozlowska ，Séverine Sarlang ，Uwe Reusch ，Stefan Knackmuss ，José Medina-Echeverz ，Joachim Koch ，Thorsten Ross ，Ali Darwich ，Lea Hoppe ，Mohammed Abba ，Alexander Streuer ，Stefan Klein ，Wolf-Karsten Hofmann ，Anna Lisa Gündner ，Christian Merz ，Jan Endell ，Jens Pahl ，Daniel Nowak

Machine learning-based in-silico analysis identifies signatures of lysyl oxidases for prognostic and therapeutic response prediction in cancer

基于机器学习的计算机模拟分析识别赖氨酰氧化酶的特征，用于预测癌症的预后和治疗反应。

期刊:Cell Communication and Signaling

影响因子:8.9

doi:10.1186/s12964-025-02176-1

Xu, Qingyu; Ma, Ling; Streuer, Alexander; Altrock, Eva; Schmitt, Nanni; Rapp, Felicitas; Klär, Alessa; Nowak, Verena; Obländer, Julia; Weimer, Nadine; Palme, Iris; Göl, Melda; Zhu, Hong-Hu; Hofmann, Wolf-Karsten; Nowak, Daniel; Riabov, Vladimir

Clinical benefit of additional whole-exome sequencing over panel sequencing in an all-comer real-world molecular tumor board

在真实世界分子肿瘤委员会中，全外显子组测序相对于panel测序的临床获益

期刊:ESMO Open

影响因子:8.3

doi:10.1016/j.esmoop.2025.105894

Krieghoff-Henning, E; Michaeli, T; Boch, T; Kirchhof, J; Haselmann, V; Neumaier, M; Hofmann, W-K; Betge, J; Ebert, M; Teufel, A; Ast, V; Sauer, C; Cotarelo, C; Lozynskyy, R; Janning, M; Marmé, F; Sütterlin, M; Streuer, A; Siegel, F; Brochhausen, C; Collienne, M; Nowak, D; Loges, S

Targeting tumoral heterogeneity in lung cancer: a novel, CT-texture-guided targeted biopsy approach with exome sequencing

针对肺癌肿瘤异质性：一种新型的基于CT纹理引导的靶向活检结合外显子组测序的方法

期刊:npj Precision Oncology

影响因子:8

doi:10.1038/s41698-025-01148-5

Hertel, Alexander; Streuer, Alexander; Diehl, Steffen; Boch, Tobias; Nörenberg, Dominik; Strittmatter, Anika; Zöllner, Frank G; Schoenberg, Stefan O; Hofmann, Wolf-Karsten; Loges, Sonja; Nowak, Daniel; Froelich, Matthias F

Primary CD34(+) cells of patients with vacuoles, E1 enzyme, X-linked, autoinflammatory, somatic (VEXAS) syndrome are highly sensitive to targeted treatment with TAK-243

患有空泡、E1酶、X连锁、自身炎症性体细胞（VEXAS）综合征的患者的原代CD34(+)细胞对TAK-243靶向治疗高度敏感。

期刊:British Journal of Haematology

影响因子:3.8

doi:10.1111/bjh.70203

Nowak, Daniel; Demmerle, Marie; Klär, Alessa; Streuer, Alexander; Riabov, Vladimir; Altrock, Eva; Rapp, Felicitas; Belzer, Ann-Christin; Klink, Teresa; Hahn, Meret; Hofmann, Franziska; Nowak, Verena; Weimer, Nadine; Obländer, Julia; Palme, Iris; Göl, Melda; Darwich, Ali; Steiner, Laurenz; Abba, Mohammed; Metzgeroth, Georgia; Hofmann, Wolf-Karsten; Schmitt, Nanni

Dynamic Mortality Risk Prediction in Myelodysplastic Syndromes Using Longitudinal Clinical Data

利用纵向临床数据对骨髓增生异常综合征进行动态死亡风险预测

期刊:JCO Clinical Cancer Informatics

影响因子:2.8

doi:10.1200/CCI-25-00236

Bobak, Jonathan; Spohr, Philipp; Richter, Sarah; Streuer, Alexander; Schulz, Felicitas Isabel; Strupp, Corinna; Gerhards, Catharina; Schmitt, Nanni; Luft, Thomas; Dietrich, Sascha; Germing, Ulrich; Klau, Gunnar W

发表日期：2025

文献求助收藏

ASXL1 mutations are associated with a response to alvocidib and 5-azacytidine combination in myelodysplastic neoplasms

ASXL1 突变与骨髓增生异常综合征患者对阿洛西地布和 5-氮杂胞苷联合治疗的反应相关。

期刊:Haematologica

影响因子:7.9

doi:10.3324/haematol.2023.282921

Riabov, Vladimir; Xu, Qingyu; Schmitt, Nanni; Streuer, Alexander; Ge, Guo; Bolanos, Lyndsey; Wunderlich, Mark; Jann, Johann-Christoph; Wein, Alina; Altrock, Eva; Demmerle, Marie; Mukherjee, Sanjay; Ali, Abdullah Mahmood; Rapp, Felicitas; Nowak, Verena; Weimer, Nadine; Obländer, Julia; Palme, Iris; Göl, Melda; Jawhar, Ahmed; Darwich, Ali; Wuchter, Patrick; Weiss, Christel; Raza, Azra; Foulks, Jason M; Starczynowski, Daniel T; Yang, Feng-Chun; Metzgeroth, Georgia; Steiner, Laurenz; Jawhar, Mohamad; Hofmann, Wolf-Karsten; Nowak, Daniel

ASXL1

发表日期：2024

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Treatment with the apoptosis inhibitor Asunercept reduces clone sizes in patients with lower risk Myelodysplastic Neoplasms

使用凋亡抑制剂阿舒那西普治疗可减少低危骨髓增生异常综合征患者的克隆大小。

期刊:Annals of Hematology

影响因子:2.4

doi:10.1007/s00277-024-05664-5

Streuer, Alexander; Jann, Johann-Christoph; Boch, Tobias; Mossner, Maximilian; Riabov, Vladimir; Schmitt, Nanni; Altrock, Eva; Xu, Qingyu; Demmerle, Marie; Nowak, Verena; Oblaender, Julia; Palme, Iris; Weimer, Nadine; Rapp, Felicitas; Metzgeroth, Georgia; Hecht, Anna; Höger, Thomas; Merz, Christian; Hofmann, Wolf-Karsten; Nolte, Florian; Nowak, Daniel

Instructive interaction between myelodysplastic hematopoiesis and the bone marrow microenvironment at the single-cell level

骨髓增生异常综合征造血与骨髓微环境在单细胞水平上的相互作用

期刊:

影响因子:

doi:10.1016/j.bneo.2024.100021

Jann, Johann-Christoph; Schmitt, Nanni; Streuer, Alexander; Xu, Qingyu; Riabov, Vladimir; Altrock, Eva; Weimer, Nadine; Nowak, Verena; Obländer, Julia; Palme, Iris; Göl, Melda; Demmerle, Marie; Rapp, Felicitas; Siegel, Fabian; Steiner, Laurenz; Ghazal, Mahmoud; Duda, Angelika; Haselmann, Verena; Darwich, Ali; Jawhar, Ahmed; Jawhar, Mohamad; Metzgeroth, Georgia; Hofmann, Wolf-Karsten; Nowak, Daniel

Gilteritinib in an Isolated CNS Recurrence of FLT3-ITD Positive AML

吉瑞替尼治疗FLT3-ITD阳性急性髓系白血病孤立性中枢神经系统复发

The bispecific innate cell engager AFM28 eliminates CD123+ leukemic stem and progenitor cells in AML and MDS

双特异性固有免疫细胞衔接器AFM28可清除急性髓系白血病（AML）和骨髓增生异常综合征（MDS）中的CD123+白血病干细胞和祖细胞。

Machine learning-based in-silico analysis identifies signatures of lysyl oxidases for prognostic and therapeutic response prediction in cancer

基于机器学习的计算机模拟分析识别赖氨酰氧化酶的特征，用于预测癌症的预后和治疗反应。

Clinical benefit of additional whole-exome sequencing over panel sequencing in an all-comer real-world molecular tumor board

在真实世界分子肿瘤委员会中，全外显子组测序相对于panel测序的临床获益

Targeting tumoral heterogeneity in lung cancer: a novel, CT-texture-guided targeted biopsy approach with exome sequencing

针对肺癌肿瘤异质性：一种新型的基于CT纹理引导的靶向活检结合外显子组测序的方法

Primary CD34(+) cells of patients with vacuoles, E1 enzyme, X-linked, autoinflammatory, somatic (VEXAS) syndrome are highly sensitive to targeted treatment with TAK-243

患有空泡、E1酶、X连锁、自身炎症性体细胞（VEXAS）综合征的患者的原代CD34(+)细胞对TAK-243靶向治疗高度敏感。

Dynamic Mortality Risk Prediction in Myelodysplastic Syndromes Using Longitudinal Clinical Data

利用纵向临床数据对骨髓增生异常综合征进行动态死亡风险预测

ASXL1 mutations are associated with a response to alvocidib and 5-azacytidine combination in myelodysplastic neoplasms

ASXL1 突变与骨髓增生异常综合征患者对阿洛西地布和 5-氮杂胞苷联合治疗的反应相关。

Treatment with the apoptosis inhibitor Asunercept reduces clone sizes in patients with lower risk Myelodysplastic Neoplasms

使用凋亡抑制剂阿舒那西普治疗可减少低危骨髓增生异常综合征患者的克隆大小。

Instructive interaction between myelodysplastic hematopoiesis and the bone marrow microenvironment at the single-cell level

骨髓增生异常综合征造血与骨髓微环境在单细胞水平上的相互作用