日期 影响因子
日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:
–

All-in-one CRISPR/Cas-engineered glucocorticoid-receptor knock-out EBV-gp350-CAR knock-in T cells are potent and resistant to dexamethasone

利用 CRISPR/Cas 技术构建的一体化糖皮质激素受体敲除 EBV-gp350-CAR 敲入 T 细胞具有高效活性且对地塞米松耐药。

期刊:Experimental Hematology & Oncology
影响因子:13.5
doi:10.1186/s40164-025-00631-w
Kaeuferle, Theresa; Zwermann, Maximilian; Stoll, Nadine; Ferrada-Ernst, Paulina; Jablonowski, Lena; Zeidler, Reinhard; Willier, Semjon; Stenger, Dana; Yassin, Abdallah; Stripecke, Renata; Feuchtinger, Tobias
信号转导
细胞生物学
T细胞
免疫/内分泌
发表日期：2025
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Integration of ζ-deficient CARs into the CD3ζ gene conveys potent cytotoxicity in T and NK cells

将缺乏 ζ 亚基的 CAR 整合到 CD3ζ 基因中，可赋予 T 细胞和 NK 细胞强大的细胞毒性。

期刊:Blood
影响因子:23.1
doi:10.1182/blood.2023020973
Kath, Jonas; Franke, Clemens; Drosdek, Vanessa; Du, Weijie; Glaser, Viktor; Fuster-Garcia, Carla; Stein, Maik; Zittel, Tatiana; Schulenberg, Sarah; Porter, Caroline E; Andersch, Lena; Künkele, Annette; Alcaniz, Joshua; Hoffmann, Jens; Abken, Hinrich; Abou-El-Enein, Mohamed; Pruß, Axel; Suzuki, Masataka; Cathomen, Toni; Stripecke, Renata; Volk, Hans-Dieter; Reinke, Petra; Schmueck-Henneresse, Michael; Wagner, Dimitrios L
T细胞
CD3
细胞生物学
NK 细胞
毒理研究
发表日期：2024
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Long-Term Human Immune Reconstitution, T-Cell Development, and Immune Reactivity in Mice Lacking the Murine Major Histocompatibility Complex: Validation with Cellular and Gene Expression Profiles

缺乏鼠主要组织相容性复合体的鼠的长期人类免疫重建、T细胞发育和免疫反应性：细胞和基因表达谱的验证

期刊:Cells
影响因子:5.2
doi:10.3390/cells13201686
Darguzyte, Milita; Antczak, Philipp; Bachurski, Daniel; Hoelker, Patrick; Abedpour, Nima; Gholamipoorfard, Rahil; Schlößer, Hans A; Wennhold, Kerstin; Thelen, Martin; Garcia-Marquez, Maria A; Koenig, Johannes; Schneider, Andreas; Braun, Tobias; Klawonn, Frank; Damrat, Michael; Rahman, Masudur; Kleid, Jan-Malte; Theobald, Sebastian J; Bauer, Eugen; von Kaisenberg, Constantin; Talbot, Steven R; Shultz, Leonard D; Soper, Brian; Stripecke, Renata
发育与干细胞
T细胞
Human
T细胞
细胞生物学
免疫/内分泌
发表日期：2024
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Review: Sustainable Clinical Development of CAR-T Cells - Switching From Viral Transduction Towards CRISPR-Cas Gene Editing

综述：CAR-T细胞的可持续临床开发——从病毒转导转向CRISPR-Cas基因编辑

期刊:Frontiers in Immunology
影响因子:5.9
doi:10.3389/fimmu.2022.865424
Wagner, Dimitrios L; Koehl, Ulrike; Chmielewski, Markus; Scheid, Christoph; Stripecke, Renata
T细胞
信号转导
微生物学
T细胞
细胞生物学
免疫/内分泌
发表日期：2022
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Correction: Repertoire characterization and validation of gB-specific human IgGs directly cloned from humanized mice vaccinated with dendritic cells and protected against HCMV

更正：对接种树突状细胞疫苗并获得HCMV保护的人源化小鼠直接克隆的gB特异性人IgG进行抗体库表征和验证

期刊:PLoS Pathogens
影响因子:4.9
doi:10.1371/journal.ppat.1009385
Theobald, Sebastian J; Kreer, Christoph; Khailaie, Sahamoddin; Bonifacius, Agnes; Eiz-Vesper, Britta; Figueiredo, Constanca; Mach, Michael; Backovic, Marija; Ballmaier, Matthias; Koenig, Johannes; Olbrich, Henning; Schneider, Andreas; Volk, Valery; Danisch, Simon; Gieselmann, Lutz; Ercanoglu, Meryem Seda; Messerle, Martin; von Kaisenberg, Constantin; Witte, Torsten; Klawonn, Frank; Meyer-Hermann, Michael; Klein, Florian; Stripecke, Renata
树突状细胞
IgG
细胞生物学
树突状细胞
免疫/内分泌
发表日期：2021
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Innovations, challenges, and minimal information for standardization of humanized mice

人源化小鼠标准化方面的创新、挑战和信息匮乏

期刊:EMBO Molecular Medicine
影响因子:8.3
doi:10.15252/emmm.201708662
Stripecke, Renata; Münz, Christian; Schuringa, Jan Jacob; Bissig, Karl-Dimiter; Soper, Brian; Meeham, Terrence; Yao, Li-Chin; Di Santo, James P; Brehm, Michael; Rodriguez, Estefania; Wege, Anja Kathrin; Bonnet, Dominique; Guionaud, Silvia; Howard, Kristina E; Kitchen, Scott; Klein, Florian; Saeb-Parsy, Kourosh; Sam, Johannes; Sharma, Amar Deep; Trumpp, Andreas; Trusolino, Livio; Bult, Carol; Shultz, Leonard
发表日期：2020
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Repertoire characterization and validation of gB-specific human IgGs directly cloned from humanized mice vaccinated with dendritic cells and protected against HCMV

对从接种树突状细胞并获得抗HCMV保护的人源化小鼠中直接克隆的gB特异性人IgG进行谱系表征和验证

期刊:PLoS Pathogens
影响因子:4.9
doi:10.1371/journal.ppat.1008560
Theobald, Sebastian J; Kreer, Christoph; Khailaie, Sahamoddin; Bonifacius, Agnes; Eiz-Vesper, Britta; Figueiredo, Constanca; Mach, Michael; Backovic, Marija; Ballmaier, Matthias; Koenig, Johannes; Olbrich, Henning; Schneider, Andreas; Volk, Valery; Danisch, Simon; Gieselmann, Lutz; Ercanoglu, Meryem Seda; Messerle, Martin; Kaisenberg, Constantin von; Witte, Torsten; Klawonn, Frank; Meyer-Hermann, Michael; Klein, Florian; Stripecke, Renata
树突状细胞
IgG
细胞生物学
树突状细胞
免疫/内分泌
发表日期：2020
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Monocytes reprogrammed with lentiviral vectors co-expressing GM-CSF, IFN-α2 and antigens for personalized immune therapy of acute leukemia pre- or post-stem cell transplantation

利用慢病毒载体对单核细胞进行重编程，使其共表达GM-CSF、IFN-α2和抗原，用于干细胞移植前后急性白血病的个性化免疫治疗。

期刊:Cancer Immunology Immunotherapy
影响因子:5.1
doi:10.1007/s00262-019-02406-9
Bialek-Waldmann, Julia K; Heuser, Michael; Ganser, Arnold; Stripecke, Renata
发育与干细胞
IFN-α
IFN-α2
白血病
微生物学
M-CSF
单核细胞
干细胞
细胞生物学
GM-CSF
免疫/内分泌
发表日期：2019
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Spatiotemporally Skewed Activation of Programmed Cell Death Receptor 1-Positive T Cells after Epstein-Barr Virus Infection and Tumor Development in Long-Term Fully Humanized Mice

Epstein-Barr病毒感染后程序性死亡受体1阳性T细胞的时空偏倚激活与长期全人源化小鼠肿瘤发展的关系

期刊:American Journal of Pathology
影响因子:3.6
doi:10.1016/j.ajpath.2018.11.014
Danisch, Simon; Slabik, Constanze; Cornelius, Angela; Albanese, Manuel; Tagawa, Takanobu; Chen, Yen-Fu A; Krönke, Nicole; Eiz-Vesper, Britta; Lienenklaus, Stefan; Bleich, Andre; Theobald, Sebastian J; Schneider, Andreas; Ganser, Arnold; von Kaisenberg, Constantin; Zeidler, Reinhard; Hammerschmidt, Wolfgang; Feuerhake, Friedrich; Stripecke, Renata
肿瘤
T细胞
肿瘤免疫
炎症/感染
信号转导
微生物学
Human
T细胞
细胞生物学
免疫/内分泌
发表日期：2019
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Signatures of T and B Cell Development, Functional Responses and PD-1 Upregulation After HCMV Latent Infections and Reactivations in Nod.Rag.Gamma Mice Humanized With Cord Blood CD34(+) Cells

脐带血CD34(+)细胞人源化Nod.Rag.Gamma小鼠HCMV潜伏感染和再激活后T细胞和B细胞发育、功能反应和PD-1上调的特征

期刊:Frontiers in Immunology
影响因子:5.9
doi:10.3389/fimmu.2018.02734
Theobald, Sebastian J; Khailaie, Sahamoddin; Meyer-Hermann, Michael; Volk, Valery; Olbrich, Henning; Danisch, Simon; Gerasch, Laura; Schneider, Andreas; Sinzger, Christian; Schaudien, Dirk; Lienenklaus, Stefan; Riese, Peggy; Guzman, Carlos A; Figueiredo, Constanca; von Kaisenberg, Constantin; Spineli, Loukia M; Glaesener, Stephanie; Meyer-Bahlburg, Almut; Ganser, Arnold; Schmitt, Michael; Mach, Michael; Messerle, Martin; Stripecke, Renata
B细胞
发育与干细胞
T细胞
炎症/感染
CD3
CD34
T细胞
Human
细胞生物学
PD-1
免疫/内分泌
发表日期：2018
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