日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

STARR-CRAAVT: A platform to identify cell type-specific regulatory elements for next-generation gene therapy

STARR-CRAAVT:用于识别下一代基因治疗的细胞类型特异性调控元件的平台

Becker, Robert; Choudhury, Priyanka; Oti, Martin; Fouani, Youssef; Strobel, Benjamin; Ketterer, Stephanie; Rumpel, Simon; Park, John; Kreuz, Sebastian; Maier, Udo; Michelfelder, Stefan; Schön, Christian

AAV yield, bioactivity, and particle heterogeneity are impacted by genome size and non-coding DNA elements

AAV的产量、生物活性和颗粒异质性受基因组大小和非编码DNA元件的影响。

Blahetek, Gina; Lindner, Benjamin; Oti, Martin; Schön, Christian; Strobel, Benjamin

Mapping administration route-dependent transduction profiles of commonly used AAV variants in mice by barcode amplicon sequencing.

通过条形码扩增子测序绘制常用 AAV 变体在小鼠体内的给药途径依赖性转导谱

Abele Sarah, Alanis-Lobato Gregorio, Oti Martin, Rust Werner, Blazevic Dragica, Danner-Liskus Jenny, Mayer Christine, Zimmermann Gudrun, Zuckschwerdt Kai, Schönberger Tanja, Gross Peter, Lempp Charlotte, Michelfelder Stefan, Strobel Benjamin

Suppression of toxic transgene expression by optimized artificial miRNAs increases AAV vector yields in HEK-293 cells

通过优化人工miRNA抑制毒性转基因表达可提高HEK-293细胞中AAV载体的产量。

Blahetek, Gina; Mayer, Christine; Zuber, Johannes; Lenter, Martin; Strobel, Benjamin

AAV-Mediated Expression of Human VEGF, TNF-α, and IL-6 Induces Retinal Pathology in Mice

AAV介导的人VEGF、TNF-α和IL-6表达可诱导小鼠视网膜病变

Weigelt, Carina M; Fuchs, Holger; Schönberger, Tanja; Stierstorfer, Birgit; Strobel, Benjamin; Lamla, Thorsten; Ciossek, Thomas; Bakker, Remko A; Redemann, Norbert H

Peripheral blood proteomic profiling of idiopathic pulmonary fibrosis biomarkers in the multicentre IPF-PRO Registry

多中心IPF-PRO注册研究中特发性肺纤维化生物标志物的外周血蛋白质组学分析

Todd, Jamie L; Neely, Megan L; Overton, Robert; Durham, Katey; Gulati, Mridu; Huang, Howard; Roman, Jesse; Newby, L Kristin; Flaherty, Kevin R; Vinisko, Richard; Liu, Yi; Roy, Janine; Schmid, Ramona; Strobel, Benjamin; Hesslinger, Christian; Leonard, Thomas B; Noth, Imre; Belperio, John A; Palmer, Scott M

Auto Poisoning of the Respiratory Chain by a Quorum-Sensing-Regulated Molecule Favors Biofilm Formation and Antibiotic Tolerance

群体感应调控分子引起的呼吸链自身中毒有利于生物膜形成和抗生素耐受性

Hazan, Ronen; Que, Yok Ai; Maura, Damien; Strobel, Benjamin; Majcherczyk, Paul Anthony; Hopper, Laura Rose; Wilbur, David J; Hreha, Teri N; Barquera, Blanca; Rahme, Laurence G