Selective and Cell-Active PBRM1 Bromodomain Inhibitors Discovered through NMR Fragment Screening
通过 NMR 片段筛选发现具有选择性和细胞活性的 PBRM1 溴结构域抑制剂
期刊:Journal of Medicinal Chemistry
影响因子:6.8
doi:10.1021/acs.jmedchem.2c00864
Shifali Shishodia, Raymundo Nuñez, Brayden P Strohmier, Karina L Bursch, Christopher J Goetz, Michael D Olp, Davin R Jensen, Tyler G Fenske, Sandra C Ordonez-Rubiano, Maya E Blau, Mallory K Roach, Francis C Peterson, Brian F Volkman, Emily C Dykhuizen, Brian C Smith
