日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Functional genomics for improving adoptive T-cell transfer therapies

利用功能基因组学改进过继性T细胞转移疗法

Skeate, Joseph G; Lee, Chang-Jung; Stewart, Carli; Fischbach, Mathew J; Kar, Bibekananda; Tsai, Alexander K; Kenderian, Saad S; Stromnes, Ingunn M; Largaespada, David A; Moriarity, Branden S; Rogers, Laura M

IL-15 Complex Enhances Agonistic Anti-CD40 + Anti-PDL1 by Correcting the T-bet to Tox Ratio in CD8+ T cells Infiltrating Pancreatic Ductal Adenocarcinoma.

IL-15 复合物通过纠正浸润胰腺导管腺癌的 CD8+ T 细胞中 T-bet 与 Tox 的比率来增强激动性抗 CD40 + 抗 PDL1 的作用

Schmiechen Zoe C, Nanda Hezkiel A, Burrack Adam L, Hickok Grant H, Butler Jonah Z, Cruz-Hinojoza Eduardo, Maurice Nicholas J, Geuenich Michael J, Yu Chengxin, Tsai Alexander K, Lonetree Cara-Lin, Ellefson Madeline A, Hilk Audrey L, Larsen Brandon M, Miller Ebony A, Rizzo Antonio B, Campbell Kieran R, Shen Steven S, Stromnes Ingunn M

IL-15 complex enhances therapeutic efficacy of anti-PD-L1 in a T cell-dependent and NK cell-independent manner in a murine model of pancreatic ductal adenocarcinoma

在小鼠胰腺导管腺癌模型中,IL-15复合物以T细胞依赖性但NK细胞非依赖性的方式增强抗PD-L1的治疗效果。

Burrack, Adam L; Tsai, Alexander K; Ellefson, Madeline A; Schmiechen, Zoe C; Larsen, Brandon M; Burrack, Kristina S; Stromnes, Ingunn M

Maturation of thymocytes with a monoclonal TCR under control of Trac promoter elements in the absence of β-selection

在缺乏β选择的情况下,单克隆TCR在Trac启动子元件的控制下,胸腺细胞的成熟

Tsai, Alexander K; Cruz-Hinojoza, Eduardo; Ellefson, Madeline A; Burrack, Adam L; Larsen, Brandon M; Martinez, Ryan J; Stromnes, Ingunn M

Trem2 Agonist Reprograms Foamy Macrophages to Promote Atherosclerotic Plaque Stability-Brief Report

Trem2激动剂重编程泡沫巨噬细胞以促进动脉粥样硬化斑块稳定性——简报

Michael T Patterson # ,Yingzheng Xu # ,Hannah Hillman # ,Victoria Osinski ,Patricia R Schrank ,Ainsley E Kennedy ,Fanta Barrow ,Alisha Zhu ,Samuel Tollison ,Sia Shekhar ,Ingunn M Stromnes ,Ilaria Tassi ,Dick Wu ,Xavier S Revelo ,Bryce A Binstadt ,Jesse W Williams

Germline T cell receptor exchange results in physiological T cell development and function

种系 T 细胞受体交换导致生理性 T 细胞发育和功能

Meagan R Rollins, Jackson F Raynor, Ebony A Miller, Jonah Z Butler, Ellen J Spartz, Walker S Lahr, Yun You, Adam L Burrack, Branden S Moriarity, Beau R Webber, Ingunn M Stromnes

Trem2 promotes foamy macrophage lipid uptake and survival in atherosclerosis

Trem2促进泡沫巨噬细胞在动脉粥样硬化中的脂质摄取和存活

Michael T Patterson ,Maria M Firulyova ,Yingzheng Xu ,Hannah Hillman ,Courtney Bishop ,Alisha Zhu ,Grant H Hickok ,Patricia R Schrank ,Christine E Ronayne ,Zakariya Caillot ,Gavin Fredrickson ,Ainsley E Kennedy ,Nisha Acharya ,Jaap G Neels ,Giulia Chinetti ,Xavier Revelo ,Ingunn M Stromnes ,Stoyan Ivanov ,Tyler D Bold ,Konstantin Zaitsev ,Jesse W Williams

Cxcr3 constrains pancreatic cancer dissemination through instructing T cell fate

Cxcr3 通过指导 T 细胞命运来限制胰腺癌的扩散

Adam L Burrack, Ellen J Spartz, Meagan R Rollins, Ebony A Miller, Maria Firulyova, Eduardo Cruz, Michael F Goldberg, Iris X Wang, Hezkiel Nanda, Steven Shen, Konstantin Zaitsev, Ingunn M Stromnes

Tumor-specific CD4 T cells instruct monocyte fate in pancreatic ductal adenocarcinoma

肿瘤特异性CD4 T细胞指导胰腺导管腺癌中单核细胞的命运

Michael T Patterson ,Adam L Burrack ,Yingzheng Xu ,Grant H Hickok ,Zoe C Schmiechen ,Samuel Becker ,Eduardo Cruz-Hinojoza ,Patricia R Schrank ,Ainsley E Kennedy ,Maria M Firulyova ,Ebony A Miller ,Konstantin Zaitsev ,Jesse W Williams ,Ingunn M Stromnes

Insufficiency of compound immune checkpoint blockade to overcome engineered T cell exhaustion in pancreatic cancer

复合免疫检查点阻断疗法不足以克服胰腺癌中基因工程改造的T细胞耗竭

Stromnes, Ingunn M; Hulbert, Ayaka; Rollins, Meagan R; Basom, Ryan S; Delrow, Jeffrey; Bonson, Patrick; Burrack, Adam L; Hingorani, Sunil R; Greenberg, Philip D