A monoclonal antibody interferes with TIMP-2 binding and incapacitates the MMP-2-activating function of multifunctional, pro-tumorigenic MMP-14/MT1-MMP.
单克隆抗体干扰 TIMP-2 结合，并使多功能促肿瘤 MMP-14/MT1-MMP 的 MMP-2 激活功能丧失能力
期刊:Oncogenesis
影响因子:6.4
doi:10.1038/oncsis.2013.44
Shiryaev S A, Remacle A G, Golubkov V S, Ingvarsen S, Porse A, Behrendt N, Cieplak P, Strongin A Y
