日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Coordinated histone modifications and chromatin reorganization in a single cell revealed by FRET biosensors

利用FRET生物传感器揭示单细胞内组蛋白修饰和染色质重组的协同作用

Peng, Qin; Lu, Shaoying; Shi, Yuxin; Pan, Yijia; Limsakul, Praopim; Chernov, Andrei V; Qiu, Juhui; Chai, Xiaoqi; Shi, Yiwen; Wang, Pengzhi; Ji, Yanmin; Li, Yi-Shuan J; Strongin, Alex Y; Verkhusha, Vladislav V; Izpisua Belmonte, Juan Carlos; Ren, Bing; Wang, Yuanliang; Chien, Shu; Wang, Yingxiao

Structural homology of myelin basic protein and muscarinic acetylcholine receptor: Significance in the pathogenesis of complex regional pain syndrome

髓鞘碱性蛋白与毒蕈碱型乙酰胆碱受体的结构同源性:在复杂区域疼痛综合征发病机制中的意义

Shubayev, Veronica I; Strongin, Alex Y; Yaksh, Tony L

Activatable and Cell-Penetrable Multiplex FRET Nanosensor for Profiling MT1-MMP Activity in Single Cancer Cells.

用于分析单个癌细胞中 MT1-MMP 活性的可激活和细胞穿透的多重 FRET 纳米传感器

Chung Eddie Y, Ochs Christopher J, Wang Yi, Lei Lei, Qin Qin, Smith Andrew M, Strongin Alex Y, Kamm Roger, Qi Ying-Xin, Lu Shaoying, Wang Yingxiao

Epigenetic inactivation of the extracellular matrix metallopeptidase ADAMTS19 gene and the metastatic spread in colorectal cancer

细胞外基质金属蛋白酶ADAMTS19基因的表观遗传失活与结直肠癌的转移扩散

Alonso, Sergio; González, Beatriz; Ruiz-Larroya, Tatiana; Durán Domínguez, Mercedes; Kato, Takaharu; Matsunaga, Akihiro; Suzuki, Koichi; Strongin, Alex Y; Gimènez-Bonafé, Pepita; Perucho, Manuel

Matrix Metalloproteinase (MMP) Proteolysis of the Extracellular Loop of Voltage-gated Sodium Channels and Potential Alterations in Pain Signaling

基质金属蛋白酶(MMP)对电压门控钠通道胞外环的蛋白水解及其对疼痛信号传导的潜在影响

Remacle, Albert G; Kumar, Sonu; Motamedchaboki, Khatereh; Cieplak, Piotr; Hullugundi, Swathi; Dolkas, Jennifer; Shubayev, Veronica I; Strongin, Alex Y

Matrix metalloproteinase-14 both sheds cell surface neuronal glial antigen 2 (NG2) proteoglycan on macrophages and governs the response to peripheral nerve injury.

基质金属蛋白酶-14 既能使巨噬细胞表面的神经元胶质抗原 2 (NG2) 蛋白聚糖脱落,又能控制周围神经损伤的反应

Nishihara Tasuku, Remacle Albert G, Angert Mila, Shubayev Igor, Shiryaev Sergey A, Liu Huaqing, Dolkas Jennifer, Chernov Andrei V, Strongin Alex Y, Shubayev Veronica I

Mycoplasma CG- and GATC-specific DNA methyltransferases selectively and efficiently methylate the host genome and alter the epigenetic landscape in human cells

支原体CG和GATC特异性DNA甲基转移酶能够选择性且高效地甲基化宿主基因组,并改变人类细胞的表观遗传图谱。

Chernov, Andrei V; Reyes, Leticia; Xu, Zhenkang; Gonzalez, Beatriz; Golovko, Georgiy; Peterson, Scott; Perucho, Manuel; Fofanov, Yuriy; Strongin, Alex Y

A humanized leucine zipper-TRAIL hybrid induces apoptosis of tumors both in vitro and in vivo

人源化亮氨酸拉链-TRAIL杂合体在体外和体内均能诱导肿瘤细胞凋亡

Rozanov, Dmitri; Spellman, Paul; Savinov, Alexei; Strongin, Alex Y

High-Throughput Multiplexed Peptide-Centric Profiling Illustrates Both Substrate Cleavage Redundancy and Specificity in the MMP Family.

高通量多重肽中心分析揭示了 MMP 家族的底物切割冗余性和特异性

Kukreja Muskan, Shiryaev Sergey A, Cieplak Piotr, Muranaka Norihito, Routenberg David A, Chernov Andrei V, Kumar Sonu, Remacle Albert G, Smith Jeffrey W, Kozlov Igor A, Strongin Alex Y

Structural and functional diversity of metalloproteinases encoded by the Bacteroides fragilis pathogenicity island

脆弱拟杆菌致病岛编码的金属蛋白酶的结构和功能多样性

Shiryaev, Sergey A; Aleshin, Alexander E; Muranaka, Norihito; Kukreja, Muskan; Routenberg, David A; Remacle, Albert G; Liddington, Robert C; Cieplak, Piotr; Kozlov, Igor A; Strongin, Alex Y