日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Time-Resolved Fluorescence Imaging and Correlative Cryo-Electron Tomography to Study Structural Changes of the HIV-1 Capsid.

利用时间分辨荧光成像和相关冷冻电镜断层扫描技术研究 HIV-1 衣壳的结构变化

Rodriguez Zaida K, Andino-Moncada Jonathan R, Buth Sergey A, Mehrani Atousa, Ranaweera Ahinsa, Shi Jincheng, Andrade Leonardo R, Singh Satya Prakash, Strutzenberg Timothy S, Marin Mariana, Guerrero-Ferreira Ricardo, Rahmani Hamid, Grotjahn Danielle A, Stagg Scott, Melikyan Gregory B, Lyumkis Dmitry, Francis Ashwanth C

Oligomeric HIV-1 integrase structures reveal functional plasticity for intasome assembly and RNA binding.

寡聚体 HIV-1 整合酶结构揭示了整合体组装和 RNA 结合的功能可塑性。

Jing Tao, Shan Zelin, Dinh Tung, Biswas Avik, Jang Sooin, Greenwood Juliet, Li Min, Zhang Zeyuan, Gray Gennavieve, Shin Hye Jeong, Zhou Bo, Passos Dario, Strutzenberg Timothy S, Aiyer Sriram, Andrade Leonardo, Zhang Yuxuan, Li Zhen, Craigie Robert, Engelman Alan N, Kvaratskhelia Mamuka, Lyumkis Dmitry

Nucleosome Engagement Regulates RORγt Structure and Dynamics.

核小体结合调节 RORγt 结构和动态

Strutzenberg Timothy S, Mann Matthew D, Li Xiandu, Shin Hyejeong, Kelsey Jordan, Aiyer Sriram, Yu Jingting, Gray Gennavieve, Zhang Zeyuan, Shan Zelin, Zhou Bo, Zheng Ye, Griffin Patrick R, Lyumkis Dmitry

Mechanisms of HIV-1 integrase resistance to dolutegravir and potent inhibition of drug-resistant variants

HIV-1整合酶对多替拉韦产生耐药性的机制以及对耐药变异株的有效抑制

Li, Min; Oliveira Passos, Dario; Shan, Zelin; Smith, Steven J; Sun, Qinfang; Biswas, Avik; Choudhuri, Indrani; Strutzenberg, Timothy S; Haldane, Allan; Deng, Nanjie; Li, Zhaoyang; Zhao, Xue Zhi; Briganti, Lorenzo; Kvaratskhelia, Mamuka; Burke, Terrence R Jr; Levy, Ronald M; Hughes, Stephen H; Craigie, Robert; Lyumkis, Dmitry

Cryo-EM structure of human GPR158 receptor coupled to the RGS7-Gβ5 signaling complex

人GPR158受体与RGS7-Gβ5信号复合物偶联的冷冻电镜结构

Patil, Dipak N; Singh, Shikha; Laboute, Thibaut; Strutzenberg, Timothy S; Qiu, Xingyu; Wu, Di; Novick, Scott J; Robinson, Carol V; Griffin, Patrick R; Hunt, John F; Izard, Tina; Singh, Appu K; Martemyanov, Kirill A

Single-Particle Cryo-EM Data Collection with Stage Tilt using Leginon

利用 Leginon 进行载物台倾斜的单颗粒冷冻电镜数据采集

Aiyer, Sriram; Strutzenberg, Timothy S; Bowman, Marianne E; Noel, Joseph P; Lyumkis, Dmitry

Structure of an AMPK complex in an inactive, ATP-bound state

处于非活性、ATP结合状态的AMPK复合物的结构

Yan, Yan; Mukherjee, Somnath; Harikumar, Kaleeckal G; Strutzenberg, Timothy S; Zhou, X Edward; Suino-Powell, Kelly; Xu, Ting-Hai; Sheldon, Ryan D; Lamp, Jared; Brunzelle, Joseph S; Radziwon, Katarzyna; Ellis, Abigail; Novick, Scott J; Vega, Irving E; Jones, Russell G; Miller, Laurence J; Xu, H Eric; Griffin, Patrick R; Kossiakoff, Anthony A; Melcher, Karsten

One-step construction of circularized nanodiscs using SpyCatcher-SpyTag

利用 SpyCatcher-SpyTag 一步构建环状纳米盘

Zhang, Shanwen; Ren, Qian; Novick, Scott J; Strutzenberg, Timothy S; Griffin, Patrick R; Bao, Huan

Recommendations for performing, interpreting and reporting hydrogen deuterium exchange mass spectrometry (HDX-MS) experiments

关于氢氘交换质谱(HDX-MS)实验的执行、解释和报告的建议

Masson, Glenn R; Burke, John E; Ahn, Natalie G; Anand, Ganesh S; Borchers, Christoph; Brier, Sébastien; Bou-Assaf, George M; Engen, John R; Englander, S Walter; Faber, Johan; Garlish, Rachel; Griffin, Patrick R; Gross, Michael L; Guttman, Miklos; Hamuro, Yoshitomo; Heck, Albert J R; Houde, Damian; Iacob, Roxana E; Jørgensen, Thomas J D; Kaltashov, Igor A; Klinman, Judith P; Konermann, Lars; Man, Petr; Mayne, Leland; Pascal, Bruce D; Reichmann, Dana; Skehel, Mark; Snijder, Joost; Strutzenberg, Timothy S; Underbakke, Eric S; Wagner, Cornelia; Wales, Thomas E; Walters, Benjamin T; Weis, David D; Wilson, Derek J; Wintrode, Patrick L; Zhang, Zhongqi; Zheng, Jie; Schriemer, David C; Rand, Kasper D

Correction: HDX-MS reveals structural determinants for RORγ hyperactivation by synthetic agonists

更正:HDX-MS揭示了合成激动剂过度激活RORγ的结构决定因素

Strutzenberg, Timothy S; Garcia-Ordonez, Ruben D; Novick, Scott J; Park, HaJeung; Chang, Mi Ra; Doebellin, Christelle; He, Yuanjun; Patouret, Rémi; Kamenecka, Theodore M; Griffin, Patrick R