日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

TAS2R5 screening reveals biased agonism that fails to evoke internalization and downregulation resulting in attenuated desensitization.

TAS2R5 筛选揭示了偏向性激动作用,未能引起内化和下调,导致脱敏作用减弱

Kim Donghwa, Strzelinski Hannah R, Liggett Stephen B

Label-free, real-time monitoring of membrane binding events at zeptomolar concentrations using frequency-locked optical microresonators

使用锁频光学微谐振器对齐摩尔浓度下的膜结合事件进行无标记实时监测

Adley Gin #, Phuong-Diem Nguyen #, Jeffrey E Melzer, Cheng Li, Hannah Strzelinski, Stephen B Liggett, Judith Su

Agonist activation to open the Gα subunit of the GPCR-G protein precoupled complex defines functional agonist activation of TAS2R5

激动剂激活以打开 GPCR-G 蛋白预偶联复合物的 Gα 亚基,这定义了 TAS2R5 的功能性激动剂激活。

Young Yang, Moon; Duy Mac, Khuong; Strzelinski, Hannah R; Hoffman, Samantha A; Kim, Donghwa; Kim, Soo-Kyung; Su, Judith; Liggett, Stephen B; Goddard, William A 3rd

Label-free, real-time monitoring of membrane binding events at zeptomolar concentrations using frequency-locked optical microresonators

利用频率锁定光学微谐振器,对浓度为泽普摩尔级的膜结合事件进行无标记实时监测

Gin, Adley; Nguyen, Phuong-Diem; Melzer, Jeffrey E; Li, Cheng; Strzelinski, Hannah; Liggett, Stephen B; Su, Judith

α1B/D-adrenoceptors regulate chemokine receptor-mediated leukocyte migration via formation of heteromeric receptor complexes

α1B/D-肾上腺素能受体通过形成异源受体复合物来调节趋化因子受体介导的白细胞迁移

Garrett A Enten, Xianlong Gao, Hannah R Strzelinski, McWayne Weche, Stephen B Liggett, Matthias Majetschak

Identification and characterization of an atypical Gαs-biased β(2)AR agonist that fails to evoke airway smooth muscle cell tachyphylaxis

鉴定和表征一种非典型Gαs偏向性β(2)肾上腺素能受体激动剂,该激动剂无法诱发气道平滑肌细胞快速耐受性

Kim, Donghwa; Tokmakova, Alina; Lujan, Lauren K; Strzelinski, Hannah R; Kim, Nicholas; Najari Beidokhti, Maliheh; Giulianotti, Marc A; Mafi, Amirhossein; Woo, Jung-A A; An, Steven S; Goddard, William A 3rd; Liggett, Stephen B