Loss of 5α-reductase type 1 accelerates the development of hepatic steatosis but protects against hepatocellular carcinoma in male mice
5α-还原酶 1 型的缺失会加速肝脏脂肪变性的发展,但可以预防雄性小鼠的肝细胞癌
期刊:Endocrinology
影响因子:3.8
doi:10.1210/en.2013-1592
Joanna K Dowman, Laurence J Hopkins, Gary M Reynolds, Matthew J Armstrong, Maryam Nasiri, Nikolaos Nikolaou, E Leonie A F van Houten, Jenny A Visser, Stuart A Morgan, Gareth G Lavery, Andrei Oprescu, Stefan G Hübscher, Philip N Newsome, Jeremy W Tomlinson