日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

A structural basis of T cell cross-reactivity to native and spliced self-antigens presented by HLA-DQ8

T细胞对HLA-DQ8呈递的天然和剪接自身抗原的交叉反应的结构基础

Mai T Tran ,Jia Jia Lim ,Tiing Jen Loh ,Stuart I Mannering ,Jamie Rossjohn ,Hugh H Reid

Glutamine deamidation does not increase the immunogenicity of C-peptide in people with type 1 diabetes

谷氨酰胺脱酰胺作用不会增加1型糖尿病患者C肽的免疫原性

Abby Foster,Pushpak Bhattacharjee,Eleonora Tresoldi,Miha Pakusch,Fergus J Cameron,Stuart I Mannering

T cell receptor recognition of hybrid insulin peptides bound to HLA-DQ8

细胞受体识别与 HLA-DQ8 结合的混合胰岛素肽

Mai T Tran, Pouya Faridi, Jia Jia Lim, Yi Tian Ting, Goodluck Onwukwe, Pushpak Bhattacharjee, Claerwen M Jones, Eleonora Tresoldi, Fergus J Cameron, Nicole L La Gruta, Anthony W Purcell, Stuart I Mannering, Jamie Rossjohn, Hugh H Reid0

CD8+ T cell landscape in Indigenous and non-Indigenous people restricted by influenza mortality-associated HLA-A*24:02 allomorph

受流感死亡率相关HLA-A*24:02同种异型限制的土著和非土著人群CD8+ T细胞图谱

Luca Hensen # ,Patricia T Illing # ,E Bridie Clemens # ,Thi H O Nguyen ,Marios Koutsakos ,Carolien E van de Sandt ,Nicole A Mifsud ,Andrea T Nguyen ,Christopher Szeto ,Brendon Y Chua ,Hanim Halim ,Simone Rizzetto ,Fabio Luciani ,Liyen Loh ,Emma J Grant ,Phillipa M Saunders ,Andrew G Brooks ,Steve Rockman ,Tom C Kotsimbos ,Allen C Cheng ,Michael Richards ,Glen P Westall ,Linda M Wakim ,Thomas Loudovaris ,Stuart I Mannering ,Michael Elliott ,Stuart G Tangye ,David C Jackson ,Katie L Flanagan ,Jamie Rossjohn ,Stephanie Gras ,Jane Davies ,Adrian Miller ,Steven Y C Tong ,Anthony W Purcell ,Katherine Kedzierska

HLA-B*27:05 alters immunodominance hierarchy of universal influenza-specific CD8+ T cells

HLA-B*27:05 改变通用流感特异性 CD8+ T 细胞的免疫优势等级

Sneha Sant ,Sergio M Quiñones-Parra ,Marios Koutsakos ,Emma J Grant ,Thomas Loudovaris ,Stuart I Mannering ,Jane Crowe ,Carolien E van de Sandt ,Guus F Rimmelzwaan ,Jamie Rossjohn ,Stephanie Gras ,Liyen Loh ,Thi H O Nguyen ,Katherine Kedzierska

Divergent SATB1 expression across human life span and tissue compartments

SATB1在人类生命周期和组织区室中的表达存在差异

Simone Nüssing ,Hui-Fern Koay ,Sneha Sant ,Thomas Loudovaris ,Stuart I Mannering ,Martha Lappas ,Yves D Udekem ,Igor E Konstantinov ,Stuart P Berzins ,Guus F Rimmelzwaan ,Stephen J Turner ,E Bridie Clemens ,Dale I Godfrey ,Thi Ho Nguyen ,Katherine Kedzierska

IFNγ-Induced MHC Class II Expression on Islet Endothelial Cells Is an Early Marker of Insulitis but Is Not Required for Diabetogenic CD4+ T Cell Migration

IFNγ 诱导的胰岛内皮细胞 MHC II 类表达是胰岛炎的早期标志,但不是糖尿病性 CD4+ T 细胞迁移所必需的

Nicholas A Scott, Yuxing Zhao, Balasubramanian Krishnamurthy, Stuart I Mannering, Thomas W H Kay, Helen E Thomas

Repurposed JAK1/JAK2 Inhibitor Reverses Established Autoimmune Insulitis in NOD Mice

重新利用的 JAK1/JAK2 抑制剂可逆转 NOD 小鼠中已建立的自身免疫性胰岛炎

Prerak M Trivedi, Kate L Graham, Nicholas A Scott, Misty R Jenkins, Suktilang Majaw, Robyn M Sutherland, Stacey Fynch, Andrew M Lew, Christopher J Burns, Balasubramanian Krishnamurthy, Thomas C Brodnicki, Stuart I Mannering, Thomas W Kay, Helen E Thomas

Mouse pancreatic beta cells express MHC class II and stimulate CD4(+) T cells to proliferate

小鼠胰腺β细胞表达MHC II类并刺激CD4(+)T细胞增殖

Yuxing Zhao, Nicholas A Scott, Hong Sheng Quah, Balasubramanian Krishnamurthy, Francene Bond, Thomas Loudovaris, Stuart I Mannering, Thomas W H Kay, Helen E Thomas

Residual methylprednisolone suppresses human T-cell responses to spleen, but not islet, extracts from deceased organ donors

残留的甲基强的松龙可抑制人类 T 细胞对来自尸体器官捐献者的脾脏(而非胰岛)提取物的反应

Max Joffe, Andra S Necula, Rochna Chand, Brett C McWhinney, Balasubramanian Krishnamurthy, Tom Loudovaris, David Goodman, Helen E Thomas, Thomas W H Kay, Stuart I Mannering