日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Gut enterochromaffin cells drive visceral pain and anxiety

肠道嗜铬细胞驱动内脏疼痛和焦虑

James R Bayrer #,Joel Castro #,Archana Venkataraman,Kouki K Touhara,Nathan D Rossen,Ryan D Morrie,Jessica Maddern,Aenea Hendry,Kristina N Braverman,Sonia Garcia-Caraballo,Gudrun Schober,Mariana Brizuela,Fernanda M Castro Navarro,Carla Bueno-Silva,Holly A Ingraham,Stuart M Brierley,David Julius

The T-type calcium channel Ca V 3.2 regulates bladder afferent responses to mechanical stimuli

型钙通道 Ca V 3.2 调节膀胱对机械刺激的传入反应

Luke Grundy, Cindy Tay, Stewart Christie, Andrea M Harrington, Joel Castro, Fernanda C Cardoso, Richard J Lewis, Vladimir Zagorodnyuk, Stuart M Brierley

Disengaging spinal afferent nerve communication with the brain in live mice

切断活体小鼠脊髓传入神经与大脑的通讯

Melinda A Kyloh #, Timothy J Hibberd #, Joel Castro, Andrea M Harrington, Lee Travis, Kelsi N Dodds, Lukasz Wiklendt, Stuart M Brierley, Vladimir P Zagorodnyuk, Nick J Spencer

TGR5 agonists induce peripheral and central hypersensitivity to bladder distension

TGR5 激动剂诱导外周和中枢对膀胱扩张的敏感性

Ashlee Caldwell #, Luke Grundy #, Andrea M Harrington, Sonia Garcia-Caraballo, Joel Castro, Nigel W Bunnett, Stuart M Brierley

Design of a Stable Cyclic Peptide Analgesic Derived from Sunflower Seeds that Targets the κ-Opioid Receptor for the Treatment of Chronic Abdominal Pain

设计一种以 κ-阿片受体为靶点的稳定环肽类镇痛药,用于治疗慢性腹痛

Edin Muratspahić, Nataša Tomašević, Johannes Koehbach, Leopold Duerrauer, Seid Hadžić, Joel Castro, Gudrun Schober, Spyridon Sideromenos, Richard J Clark, Stuart M Brierley, David J Craik, Christian W Gruber

Pharmacological Inhibition of the Voltage-Gated Sodium Channel NaV1.7 Alleviates Chronic Visceral Pain in a Rodent Model of Irritable Bowel Syndrome

电压门控钠通道 NaV1.7 的药理学抑制可缓解肠易激综合征啮齿动物模型中的慢性内脏痛

Yan Jiang, Joel Castro, Linda V Blomster, Akello J Agwa, Jessica Maddern, Gudrun Schober, Volker Herzig, Chun Yuen Chow, Fernanda C Cardoso, Paula Demétrio De Souza França, Junior Gonzales, Christina I Schroeder, Steffen Esche, Thomas Reiner, Stuart M Brierley, Glenn F King

Activation of MrgprA3 and MrgprC11 on Bladder-Innervating Afferents Induces Peripheral and Central Hypersensitivity to Bladder Distension

膀胱支配传入神经上 MrgprA3 和 MrgprC11 的激活诱发对膀胱扩张的外周和中枢过敏

Luke Grundy, Ashlee Caldwell, Sonia Garcia-Caraballo, David Grundy, Nick J Spencer, Xinzhong Dong, Joel Castro, Andrea M Harrington, Stuart M Brierley

Experimentally Induced Bladder Permeability Evokes Bladder Afferent Hypersensitivity in the Absence of Inflammation

实验诱导的膀胱通透性在没有炎症的情况下引起膀胱传入神经过敏

Luke Grundy, Ashlee Caldwell, Amanda Lumsden, Ehsan Mohammadi, Gerhard Hannig, Beverley Greenwood Van-Meervald, Stuart M Brierley

Purinergic receptor mediated calcium signalling in urothelial cells

尿路上皮细胞中嘌呤受体介导的钙信号传导

Russell Chess-Williams, Donna J Sellers, Stuart M Brierley, David Grundy, Luke Grundy

Co-expression of μ and δ opioid receptors by mouse colonic nociceptors

小鼠结肠痛觉感受器中 μ 和 δ 阿片受体的共表达

Raquel Guerrero-Alba, Eduardo Emmanuel Valdez-Morales, Nestor Nivardo Jiménez-Vargas, Romke Bron, Daniel Poole, David Reed, Joel Castro, Melissa Campaniello, Patrick A Hughes, Stuart M Brierley, Nigel Bunnett, Alan E Lomax, Stephen Vanner