日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Generation of induced pluripotent stem cells (iPSCs) from a hypertrophic cardiomyopathy patient with the pathogenic variant p.Val698Ala in beta-myosin heavy chain (MYH7) gene

从患有 β-肌球蛋白重链 (MYH7) 基因致病变异 p.Val698Ala 的肥厚性心肌病患者体内生成诱导性多能干细胞 (iPSC)

Samantha Barratt Ross, Stuart T Fraser, Natalie Nowak, Christopher Semsarian

Peripheral blood derived induced pluripotent stem cells (iPSCs) from a female with familial hypertrophic cardiomyopathy

来自家族性肥厚型心肌病女性的外周血诱导性多能干细胞 (iPSC)

Samantha Barratt Ross, Stuart T Fraser, Richard D Bagnall, Christopher Semsarian

Expression of podocalyxin separates the hematopoietic and vascular potentials of mouse embryonic stem cell-derived mesoderm

足糖萼蛋白的表达分离了小鼠胚胎干细胞衍生的中胚层的造血和血管潜能

Hailan Zhang, Johnathan L Nieves, Stuart T Fraser, Joan Isern, Panagiotis Douvaras, Dmitri Papatsenko, Sunita L D'Souza, Ihor R Lemischka, Michael A Dyer, Margaret H Baron

Mutant human FUS Is ubiquitously mislocalized and generates persistent stress granules in primary cultured transgenic zebrafish cells

突变的人类 FUS 普遍存在错误定位,并在原代培养的转基因斑马鱼细胞中产生持续的应激颗粒

Jamie Rae Acosta, Claire Goldsbury, Claire Winnick, Andrew P Badrock, Stuart T Fraser, Angela S Laird, Thomas E Hall, Emily K Don, Jennifer A Fifita, Ian P Blair, Garth A Nicholson, Nicholas J Cole

Hes repressors are essential regulators of hematopoietic stem cell development downstream of Notch signaling

Hes 阻遏物是 Notch 信号下游造血干细胞发育的重要调节因子

Jordi Guiu, Ritsuko Shimizu, Teresa D'Altri, Stuart T Fraser, Jun Hatakeyama, Emery H Bresnick, Ryoichiro Kageyama, Elaine Dzierzak, Masayuki Yamamoto, Lluis Espinosa, Anna Bigas

The CACCC-binding protein KLF3/BKLF represses a subset of KLF1/EKLF target genes and is required for proper erythroid maturation in vivo

CACCC 结合蛋白 KLF3/BKLF 抑制了 KLF1/EKLF 靶基因的一个子集,并且是体内红细胞正常成熟所必需的

Alister P W Funnell, Laura J Norton, Ka Sin Mak, Jon Burdach, Crisbel M Artuz, Natalie A Twine, Marc R Wilkins, Carl A Power, Tzong-Tyng Hung, José Perdomo, Philip Koh, Kim S Bell-Anderson, Stuart H Orkin, Stuart T Fraser, Andrew C Perkins, Richard C M Pearson, Merlin Crossley

Intra-aortic clusters undergo endothelial to hematopoietic phenotypic transition during early embryogenesis

主动脉内簇在早期胚胎发生过程中经历内皮到造血表型的转变

Chiyo Mizuochi, Stuart T Fraser, Katia Biasch, Yuka Horio, Yoshikane Kikushige, Kenzaburo Tani, Koichi Akashi, Manuela Tavian, Daisuke Sugiyama

Dose-dependent regulation of primitive erythroid maturation and identity by the transcription factor Eklf

转录因子 Eklf 对原始红细胞成熟和身份的剂量依赖性调节

Joan Isern, Stuart T Fraser, Zhiyong He, Hailan Zhang, Margaret H Baron

Transcriptional activation by the Mixl1 homeodomain protein in differentiating mouse embryonic stem cells

Mixl1 同源域蛋白在小鼠胚胎干细胞分化中的转录激活

Hailan Zhang, Stuart T Fraser, Cristian Papazoglu, Maureen E Hoatlin, Margaret H Baron

Acceleration of mesoderm development and expansion of hematopoietic progenitors in differentiating ES cells by the mouse Mix-like homeodomain transcription factor

小鼠 Mix 样同源域转录因子加速中胚层发育和造血祖细胞扩增,促进 ES 细胞分化

Stephen Willey, Angel Ayuso-Sacido, Hailan Zhang, Stuart T Fraser, Kenneth E Sahr, Matthew J Adlam, Michael Kyba, George Q Daley, Gordon Keller, Margaret H Baron