日期 影响因子
日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:
–

Discovery of SD-436: A Potent, Highly Selective and Efficacious STAT3 PROTAC Degrader Capable of Achieving Complete and Long-Lasting Tumor Regression

SD-436 的发现：一种强效、高选择性和高效的 STAT3 PROTAC 降解剂，能够实现完全且持久的肿瘤消退

期刊:Journal of Medicinal Chemistry
影响因子:6.8
doi:10.1021/acs.jmedchem.4c01946
Xu, Renqi; Zhou, Haibin; Bai, Longchuan; McEachern, Donna; Wu, Dimin; Acharyya, Ranjan Kumar; Wang, Mi; Tošović, Jelena; Yang, Chao-Yie; Chinnaswamy, Krishnapriya; Meagher, Jennifer L; Stuckey, Jeanne A; Liu, Cai; Wang, Meilin; Wen, Bo; Sun, Duxin; Wang, Shaomeng
JAK/STAT
STAT3
肿瘤
肿瘤免疫
发表日期：2024
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Comprehensive Analyses of the Effects of the Small-Molecule Inhibitor of the UHM Domain in the Splicing Factor U2AF1 in Leukemia Cells

对白血病细胞中剪接因子U2AF1的UHM结构域小分子抑制剂作用的综合分析

期刊:
影响因子:
doi:10.21203/rs.3.rs-4477663/v1
Yuan, Xinrui; Sabzvar, Mona Kazemi; Patil, Amol D; Chinnaswamy, Krishnapriya; Howie, Kathryn L; Andhavaram, Ramaraju; Wang, Borwyn; Siegler, Maxime A; Dumaz, Arda; Stuckey, Jeanne A; Corey, Seth J; Maciejewski, Jaroslaw P; Visconte, Valeria; Yang, Chao-Yie
白血病
细胞生物学
U2AF1
发表日期：2024
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Correction to "Profiling the Binding Activities of Peptides and Inhibitors to the U2 Auxiliary Factor Homology Motif (UHM) Domains"

对“肽和抑制剂与U2辅助因子同源基序（UHM）结构域的结合活性分析”一文的更正

期刊:ACS Medicinal Chemistry Letters
影响因子:4
doi:10.1021/acsmedchemlett.3c00123
Yuan, Xinrui; Howie, Kathryn L; Kazemi Sabzvar, Mona; Chinnaswamy, Krishnapriya; Stuckey, Jeanne A; Yang, Chao-Yie
发表日期：2023
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Profiling the Binding Activities of Peptides and Inhibitors to the U2 Auxiliary Factor Homology Motif (UHM) Domains

肽和抑制剂与U2辅助因子同源基序（UHM）结构域结合活性的分析

期刊:ACS Medicinal Chemistry Letters
影响因子:4
doi:10.1021/acsmedchemlett.2c00537
Yuan, Xinrui; Howie, Kathryn L; Kazemi Sabzvar, Mona; Chinnaswamy, Krishnapriya; Stuckey, Jeanne A; Yang, Chao-Yie
发表日期：2023
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Structure-Activity relationship of 1-(Furan-2ylmethyl)Pyrrolidine-Based Stimulation-2 (ST2) inhibitors for treating graft versus host disease

1-(呋喃-2-基甲基)吡咯烷类刺激-2 (ST2) 抑制剂治疗移植物抗宿主病的构效关系

期刊:Bioorganic & Medicinal Chemistry
影响因子:3
doi:10.1016/j.bmc.2022.116942
Yuan, Xinrui; Jiang, Hua; Fu, Denggang; Robida, Aaron; Rajanayake, Krishani; Yuan, Hebao; Wen, Bo; Sun, Duxin; Watch, Brennan T; Chinnaswamy, Krishnapriya; Stuckey, Jeanne A; Paczesny, Sophie; Rech, Jason C; Yang, Chao-Yie
发表日期：2022
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Open Reading Frame 1 Protein of the Human Long Interspersed Nuclear Element 1 Retrotransposon Binds Multiple Equivalents of Lead

人类长散在核元件1逆转录转座子的开放阅读框1蛋白结合多个铅当量

期刊:Journal of the American Chemical Society
影响因子:15.6
doi:10.1021/jacs.1c06461
Pinter, Tyler B J; Ruckthong, Leela; Stuckey, Jeanne A; Deb, Aniruddha; Penner-Hahn, James E; Pecoraro, Vincent L
Human
发表日期：2021
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Discovery of Potent Small-Molecule Inhibitors of MLL Methyltransferase

发现MLL甲基转移酶的强效小分子抑制剂

期刊:ACS Medicinal Chemistry Letters
影响因子:4
doi:10.1021/acsmedchemlett.0c00229
Chern, Ting-Rong; Liu, Liu; Petrunak, Elyse; Stuckey, Jeanne A; Wang, Mi; Bernard, Denzil; Zhou, Haibin; Lee, Shirley; Dou, Yali; Wang, Shaomeng
发表日期：2020
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Structure of the zinc-finger antiviral protein in complex with RNA reveals a mechanism for selective targeting of CG-rich viral sequences

锌指抗病毒蛋白与RNA复合物的结构揭示了其选择性靶向富含CG序列的病毒序列的机制。

期刊:Proceedings of the National Academy of Sciences of the United States of America
影响因子:9.1
doi:10.1073/pnas.1913232116
Meagher, Jennifer L; Takata, Matthew; Gonçalves-Carneiro, Daniel; Keane, Sarah C; Rebendenne, Antoine; Ong, Heley; Orr, Victoria K; MacDonald, Margaret R; Stuckey, Jeanne A; Bieniasz, Paul D; Smith, Janet L
微生物学
发表日期：2019
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How Outer Coordination Sphere Modifications Can Impact Metal Structures in Proteins: A Crystallographic Evaluation

外配位层修饰如何影响蛋白质中的金属结构：晶体学评价

期刊:Chemistry-A European Journal
影响因子:3.7
doi:10.1002/chem.201806040
Ruckthong, Leela; Stuckey, Jeanne A; Pecoraro, Vincent L
发表日期：2019
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Differential Conformational Dynamics Encoded by the Linker between Quasi RNA Recognition Motifs of Heterogeneous Nuclear Ribonucleoprotein H

异质核糖核蛋白H准RNA识别基序之间的连接子编码的差异构象动力学

期刊:Journal of the American Chemical Society
影响因子:15.6
doi:10.1021/jacs.8b05366
Penumutchu, Srinivasa R; Chiu, Liang-Yuan; Meagher, Jennifer L; Hansen, Alexandar L; Stuckey, Jeanne A; Tolbert, Blanton S
发表日期：2018
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