Targeting a Glutamic Acid in PDEδ with Fluoromethyl-Aryl Electrophiles Impairs K-Ras Signaling
用氟甲基-芳基亲电试剂靶向PDEδ中的谷氨酸会损害K-Ras信号传导
期刊:Journal of Medicinal Chemistry
影响因子:6.8
doi:10.1021/acs.jmedchem.5c02082
Zhang, Ruirui; Huetzen, Maxim A; Binici, Aylin; Martín-Gago, Pablo; Gasper, Raphael; Rudashevskaya, Elena; Liu, Jie; Nagaraju, Chinta; Reckzeh, Elena S; Stuedle, Alana S T; Hopff, Ann-Sophie; Mesaros, Andrea; Unger, Anke; Thelen, Melanie; Janning, Petra; Reinhardt, H Christian; Ziegler, Slava; Jachimowicz, Ron D; Waldmann, Herbert
