日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Variants of Unknown Significance in Genes Associated with Heritable Thoracic Aortic Disease Can Be Low Penetrant "Risk Variants"

与遗传性胸主动脉疾病相关的基因中意义不明的变异可能是低外显率的“风险变异”。

Kwartler, Callie S; Gong, Limin; Chen, Jiyuan; Wang, Shanzhi; Kulmacz, Richard; Duan, Xue-Yan; Janda, Alexandra; Huang, Jian; Kamm, Kristine E; Stull, James T; Guo, Dongchuan; Milewicz, Dianna M

The dominant protein phosphatase PP1c isoform in smooth muscle cells, PP1cβ, is essential for smooth muscle contraction

平滑肌细胞中主要的蛋白磷酸酶PP1c亚型PP1cβ对于平滑肌收缩至关重要。

Chang, Audrey N; Gao, Ning; Liu, Zhenan; Huang, Jian; Nairn, Angus C; Kamm, Kristine E; Stull, James T

Genetic approaches to identify pathological limitations in aortic smooth muscle contraction

利用遗传学方法识别主动脉平滑肌收缩的病理限制

Huang, Jian; Gao, Ning; Wang, Shanzhi; Milewicz, Dianna M; Kamm, Kristine E; Stull, James T

Altered Smooth Muscle Cell Force Generation as a Driver of Thoracic Aortic Aneurysms and Dissections

平滑肌细胞力生成改变是胸主动脉瘤和夹层的驱动因素

Milewicz, Dianna M; Trybus, Kathleen M; Guo, Dong-Chuan; Sweeney, H Lee; Regalado, Ellen; Kamm, Kristine; Stull, James T

Role of myosin light chain phosphatase in cardiac physiology and pathophysiology

肌球蛋白轻链磷酸酶在心脏生理和病理生理中的作用

Chang, Audrey N; Kamm, Kristine E; Stull, James T

Signaling through myosin light chain kinase in smooth muscles

平滑肌中肌球蛋白轻链激酶的信号传导

Gao, Ning; Huang, Jian; He, Weiqi; Zhu, Minsheng; Kamm, Kristine E; Stull, James T

Rare, nonsynonymous variant in the smooth muscle-specific isoform of myosin heavy chain, MYH11, R247C, alters force generation in the aorta and phenotype of smooth muscle cells.

肌球蛋白重链平滑肌特异性亚型 MYH11 的罕见非同义变异 R247C 会改变主动脉的力生成和平滑肌细胞的表型

Kuang Shao-Qing, Kwartler Callie S, Byanova Katerina L, Pham John, Gong Limin, Prakash Siddharth K, Huang Jian, Kamm Kristine E, Stull James T, Sweeney H Lee, Milewicz Dianna M

Role of myosin light chain kinase in regulation of basal blood pressure and maintenance of salt-induced hypertension.

肌球蛋白轻链激酶在调节基础血压和维持盐诱导性高血压中的作用

He Wei-Qi, Qiao Yan-Ning, Zhang Cheng-Hai, Peng Ya-Jing, Chen Chen, Wang Pei, Gao Yun-Qian, Chen Caiping, Chen Xin, Tao Tao, Su Xiao-Hong, Li Chao-Jun, Kamm Kristine E, Stull James T, Zhu Min-Sheng

Signaling to myosin regulatory light chain in sarcomeres

肌节中肌球蛋白调节轻链的信号传导

Kamm, Kristine E; Stull, James T

Thematic minireview series on signaling in cardiac sarcomeres in health and disease

关于健康和疾病状态下心肌肌节信号传导的专题小型综述系列

Solaro, R John; Stull, James T