文献库，生知库 | 链接生命科学的每一步

TNF-α and α-synuclein fibrils differently regulate human astrocyte immune reactivity and impair mitochondrial respiration

TNF-α 和 α-突触核蛋白原纤维以不同的方式调节人类星形胶质细胞的免疫反应并损害线粒体呼吸

doi:10.1016/j.celrep.2021.108895

Kaspar Russ, Gabriel Teku, Luc Bousset, Virginie Redeker, Sara Piel, Ekaterina Savchenko, Yuriy Pomeshchik, Jimmy Savistchenko, Tina C Stummann, Carla Azevedo, Anna Collin, Stefano Goldwurm, Karina Fog, Eskil Elmer, Mauno Vihinen, Ronald Melki, Laurent Roybon

Establishment of a human induced pluripotent stem cell neuronal model for identification of modulators of A53T α-synuclein levels and aggregation

建立人诱导多能干细胞神经元模型，用于鉴定A53T α-突触核蛋白水平和聚集的调节因子

期刊:PLoS One

影响因子:2.9

doi:10.1371/journal.pone.0261536

Charlotte Vajhøj ，Benjamin Schmid ，Ania Alik ，Ronald Melki ，Karina Fog ，Bjørn Holst ，Tina Charlotte Stummann

Alpha7 nicotinic acetylcholine receptors and neural network synaptic transmission in human induced pluripotent stem cell-derived neurons

人类诱导性多能干细胞衍生神经元中的 Alpha7 烟碱乙酰胆碱受体和神经网络突触传递

期刊:Stem Cell Research

影响因子:0.8

doi:10.1016/j.scr.2019.101642

Hjalte M Larsen, Susanne K Hansen, Jens D Mikkelsen, Poul Hyttel, Tina C Stummann

Patient iPSC-Derived Neurons for Disease Modeling of Frontotemporal Dementia with Mutation in CHMP2B

利用患者诱导多能干细胞衍生的神经元构建CHMP2B基因突变引起的额颞叶痴呆疾病模型

期刊:Stem Cell Reports

影响因子:5.1

doi:10.1016/j.stemcr.2017.01.012

Zhang, Yu; Schmid, Benjamin; Nikolaisen, Nanett K; Rasmussen, Mikkel A; Aldana, Blanca I; Agger, Mikkel; Calloe, Kirstine; Stummann, Tina C; Larsen, Hjalte M; Nielsen, Troels T; Huang, Jinrong; Xu, Fengping; Liu, Xin; Bolund, Lars; Meyer, Morten; Bak, Lasse K; Waagepetersen, Helle S; Luo, Yonglun; Nielsen, Jørgen E; Holst, Bjørn; Clausen, Christian; Hyttel, Poul; Freude, Kristine K

Transient p53 suppression increases reprogramming of human fibroblasts without affecting apoptosis and DNA damage

暂时的 p53 抑制可增加人类成纤维细胞的重编程，而不会影响细胞凋亡和 DNA 损伤

期刊:Stem Cell Reports

影响因子:5.9

doi:10.1016/j.stemcr.2014.07.006

Mikkel A Rasmussen, Bjørn Holst, Zeynep Tümer, Mads G Johnsen, Shuling Zhou, Tina C Stummann, Poul Hyttel, Christian Clausen

The diversity of perinuclear antineutrophil cytoplasmic antibodies (pANCA) antigens

核周抗中性粒细胞胞浆抗体（pANCA）抗原的多样性

期刊:Clinical and Experimental Immunology

影响因子:3.8

doi:10.1111/j.1365-2249.1995.tb06155.x

Wiik, A; Stummann, L; Kjeldsen, L; Borregaard, N; Ullman, S; Jacobsen, S; Halberg, P

USP30 inhibition induces mitophagy and reduces oxidative stress in parkin-deficient human neurons

USP30 抑制可诱导线粒体自噬并减少 parkin 缺乏的人类神经元中的氧化应激

TNF-α and α-synuclein fibrils differently regulate human astrocyte immune reactivity and impair mitochondrial respiration

TNF-α 和 α-突触核蛋白原纤维以不同的方式调节人类星形胶质细胞的免疫反应并损害线粒体呼吸

Establishment of a human induced pluripotent stem cell neuronal model for identification of modulators of A53T α-synuclein levels and aggregation

建立人诱导多能干细胞神经元模型，用于鉴定A53T α-突触核蛋白水平和聚集的调节因子

Alpha7 nicotinic acetylcholine receptors and neural network synaptic transmission in human induced pluripotent stem cell-derived neurons

人类诱导性多能干细胞衍生神经元中的 Alpha7 烟碱乙酰胆碱受体和神经网络突触传递

Patient iPSC-Derived Neurons for Disease Modeling of Frontotemporal Dementia with Mutation in CHMP2B

利用患者诱导多能干细胞衍生的神经元构建CHMP2B基因突变引起的额颞叶痴呆疾病模型

Transient p53 suppression increases reprogramming of human fibroblasts without affecting apoptosis and DNA damage

暂时的 p53 抑制可增加人类成纤维细胞的重编程，而不会影响细胞凋亡和 DNA 损伤

The diversity of perinuclear antineutrophil cytoplasmic antibodies (pANCA) antigens

核周抗中性粒细胞胞浆抗体（pANCA）抗原的多样性