Discovery of GNE-6893, a Potent, Selective, Orally Bioavailable Small Molecule Inhibitor of HPK1
发现GNE-6893,一种高效、选择性强、口服生物利用度高的HPK1小分子抑制剂
期刊:ACS Medicinal Chemistry Letters
影响因子:4
doi:10.1021/acsmedchemlett.4c00319
Tellis, John C; Wei, BinQing; Siu, Michael; An, Le; Chan, Grace Kayan; Chen, Yong; Du, Xiangnan; Gazzard, Lewis; Hu, Baihua; Kiefer, James; Kakiuchi-Kiyota, Satoko; Lainchbury, Michael; Linehan, Jonathan L; Luo, Xifeng; Malhotra, Sushant; Mendonca, Rohan; Pang, Jodie; Ran, Yinqing; Sethuraman, Vijay; Seward, Eileen; Sneeringer, Chris; Su, Dian; Wang, Weiru; Wu, Ping; Moffat, John G; Heffron, Timothy P; Choo, Edna F; Chan, Bryan K