A novel photosensitizer berberine derivative B12 induces apoptosis and suppresses HIF-1α expression in colorectal cancer cells via mitochondria-to-nucleus sequential-targeting
一种新型光敏剂小檗碱衍生物B12通过线粒体到细胞核的顺序靶向作用诱导结直肠癌细胞凋亡并抑制HIF-1α表达。
期刊:Acta Pharmacologica Sinica
影响因子:8.4
doi:10.1038/s41401-025-01728-y
Pei, Wen-Bin; Lei, Zi-Yu; Xie, Fu-Quan; Chen, Peng; Su, Yong-Cheng; Qin, Yu-Shan; Li, Jiang-Quan; Shen, Qian-Wen; Ma, Miao-Miao; Gao, Chun-Yi; Zhu, Jia-Chen; Xu, Ya-Jie; Zhang, Kai-Yue; Zhang, Wen-Qing; Zhang, Yan-Dong; Hu, Tian-Hui; Xu, Bei-Bei
