文献库，生知库 | 链接生命科学的每一步

日期影响因子

MSDC-0160, a novel clinical-stage mitochondrial pyruvate carrier inhibitor, suppresses osteoclast differentiation and alleviates type 2 diabetes-related bone loss

MSDC-0160 是一种新型的临床阶段线粒体丙酮酸载体抑制剂，可抑制破骨细胞分化并减轻 2 型糖尿病相关的骨质流失。

期刊:Journal of Translational Medicine

影响因子:7.5

doi:10.1186/s12967-026-07699-w

Wang, Chaofeng; Hai, Na; Chen, Liuyuan; Huang, Qian; Gui, Ying; Su, Yuangang; Lian, Haoyu; Liang, Jiamin; Zhao, Jinmin; Xu, Jiake; Liu, Qian

多发性硬化症

细胞生物学

发表日期：2026

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Correction: Periplogenin attenuates LPS-mediated inflammatory osteolysis through the suppression of osteoclastogenesis via reducing the NF-κB and MAPK signaling pathways

更正：Periplogenin 通过抑制破骨细胞生成，进而降低 NF-κB 和 MAPK 信号通路，从而减弱 LPS 介导的炎症性骨溶解。

期刊:Cell Death Discovery

doi:10.1038/s41420-026-03007-z

Gan, Kai; Lian, Haoyu; Yang, Tao; Huang, Jian; Chen, Junchun; Su, Yuangang; Zhao, Jinmin; Xu, Jiake; Liu, Qian

细胞生物学

发表日期：2026

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Machine learning and AI-Assisted red blood cell morphology analysis for effective thalassemia screening

利用机器学习和人工智能辅助的红细胞形态分析进行有效的地中海贫血筛查

期刊:Annals of Hematology

影响因子:2.4

doi:10.1007/s00277-026-06860-1

Gui, Ying; Chen, Weiwei; Su, Yuangang; Qin, Caizhen; Zhang, Fuyong; Zhao, Jinmin; Liu, Qian

细胞生物学

发表日期：2026

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Sinensetin serves as an AMPK activator to inhibit RANKL-induced osteoclastogenesis via osteoclast cytoskeleton reorganization.

川陈皮素作为 AMPK 激活剂，通过破骨细胞骨架重组抑制 RANKL 诱导的破骨细胞生成

期刊:Journal of Translational Medicine

影响因子:7.5

doi:10.1186/s12967-025-06708-8

Gao Yijie, Zhou Rui, Lin Xixi, Liu Zhijuan, Su Yuangang, Lian Haoyu, Lin Bin, Ding Xiaofei, Liao Shijie, Li Xiangde, Zhao Jinmin, Xu Jiake, Xu Ren, Liu Qian, Song Fangming

细胞生物学

发表日期：2025

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Carnosic acid serves as a dual Nrf2 activator and PTEN/AKT suppressor to inhibit traumatic heterotopic ossification

鼠尾草酸作为Nrf2激活剂和PTEN/AKT抑制剂，可抑制创伤性异位骨化。

期刊:Stem Cell Research & Therapy

影响因子:7.3

doi:10.1186/s13287-025-04886-2

Wei, Donglei; Song, Dezhi; Wang, Hui; Su, Yuangang; Liang, Jiamin; Xu, Jiake; Zhao, Jinmin; Liu, Qian

发表日期：2025

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Transcriptomic analysis reveals TME-mediated macrophage IFIT1 upregulation and CX3CR1 suppression drive osteosarcoma progression

转录组分析揭示肿瘤微环境介导的巨噬细胞IFIT1上调和CX3CR1抑制驱动骨肉瘤进展

期刊:Frontiers in Oncology

影响因子:3.3

doi:10.3389/fonc.2025.1686854

Wang, Keyi; He, Huanyang; Liang, Jiamin; Su, Yuangang; Zhao, Jinmin; Liu, Qian

细胞生物学

肿瘤微环境

免疫/内分泌

发表日期：2025

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Periplogenin attenuates LPS-mediated inflammatory osteolysis through the suppression of osteoclastogenesis via reducing the NF-κB and MAPK signaling pathways

Periplogenin通过抑制破骨细胞生成，降低NF-κB和MAPK信号通路，从而减轻LPS介导的炎症性骨溶解。

期刊:Cell Death Discovery

doi:10.1038/s41420-024-01856-0

Gan, Kai; Lian, Haoyu; Yang, Tao; Huang, Jian; Chen, Junchun; Su, Yuangang; Zhao, Jinmin; Xu, Jiake; Liu, Qian

细胞生物学

发表日期：2024

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Cichoric acid targets RANKL to inhibit osteoclastogenesis and prevent ovariectomy-induced bone loss

菊苣酸靶向 RANKL 来抑制破骨细胞生成并预防卵巢切除术引起的骨质流失

期刊:Phytotherapy Research

影响因子:6.1

doi:10.1002/ptr.8141

Yansi Xian, Yijie Gao, Yiji Su, Yuangang Su, Haoyu Lian, Xiaoliang Feng, Zhijuan Liu, Jinmin Zhao, Jiake Xu, Qian Liu, Fangming Song

细胞生物学

发表日期：2024

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Comparisons of Forecasting for Survival Outcome for Head and Neck Squamous Cell Carcinoma by using Machine Learning Models based on Multi-omics

基于多组学的机器学习模型对头颈部鳞状细胞癌生存结局预测的比较

期刊:Current Genomics

影响因子:1.4

doi:10.2174/1389202923666220204153744

Mo, Liying; Su, Yuangang; Yuan, Jianhui; Xiao, Zhiwei; Zhang, Ziyan; Lan, Xiuwan; Huang, Daizheng

细胞生物学

发表日期：2022

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Vindoline Inhibits RANKL-Induced Osteoclastogenesis and Prevents Ovariectomy-Induced Bone Loss in Mice

长春碱抑制RANKL诱导的破骨细胞生成并预防小鼠卵巢切除术引起的骨丢失

期刊:Frontiers in Pharmacology

影响因子:4.8

doi:10.3389/fphar.2019.01587

Zhan, Yunfei; Liang, Jiamin; Tian, Kun; Che, Zhigang; Wang, Ziyi; Yang, Xue; Su, Yuangang; Lin, Xixi; Song, Fangming; Zhao, Jinmin; Xu, Jiake; Liu, Qian; Zhou, Bo

细胞生物学

发表日期：2019

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