日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Immune cell clustering identifies a CD163⁺/CSF1R⁺ macrophage and neutrophil-enriched phenotype with distinct biological signatures and poor prognosis in angiosarcoma

免疫细胞聚类分析可识别出一种富含CD163⁺/CSF1R⁺巨噬细胞和中性粒细胞的表型,该表型具有独特的生物学特征,且在血管肉瘤中预后不良。

Simon, Adrian Georg; Grothey, Bastian; Lyu, Su Ir; Stahl, David; Schiffmann, Lars Mortimer; Bruns, Christiane Josephine; Eysel, Peer; Buettner, Reinhard; Ullrich, Roland Tillmann; Quaas, Alexander

Schlafen 11 as a prognostic and potentially predictive biomarker in soft tissue sarcoma: evidence from a real-world cohort

Schlafen 11 作为软组织肉瘤的预后和潜在预测生物标志物:来自真实世界队列的证据

Simon, Adrian Georg; Lyu, Su Ir; Stahl, David; Schiffmann, Lars Mortimer; Wenk, Birte; Buettner, Reinhard; Wuerdemann, Nora; Tuchscherer, Armin; Ullrich, Roland Tillmann; Quaas, Alexander

Proteomic characterization of MET-amplified esophageal adenocarcinomas reveals enrichment of alternative splicing- and androgen signaling-related proteins

对MET扩增的食管腺癌进行蛋白质组学分析发现,其富集了与选择性剪接和雄激素信号传导相关的蛋白质。

Grothey, Bastian; Lyu, Su Ir; Quaas, Alexander; Simon, Adrian Georg; Jung, Jin-On; Schröder, Wolfgang; Bruns, Christiane J; Schiffmann, Lars M; Popp, Felix C; Schmidt, Thomas; Knipper, Karl

Adjuvant FLOT provides survival benefit for oesophagogastric junction and gastric adenocarcinoma patients with low tumour regression after neoadjuvant chemotherapy

对于新辅助化疗后肿瘤消退程度低的食管胃交界处癌和胃腺癌患者,辅助性FLOT方案可带来生存获益。

Kraemer, Max; Wirsik, Naita M; Alakus, Hakan; Schloesser, Hans A; Fuchs, Hans; Schroeder, Wolfgang; Bruns, Christiane J; Lyu, Su Ir; Baehr, Friederike; Zander, Thomas; Quaas, Alexander

Exploration of histone protein γ-H2AX as a prognostic factor in soft tissue sarcomas and its association with biological behavior, immune cell environment and survival in leiomyosarcoma.

探索组蛋白 α-H2AX 作为软组织肉瘤的预后因素及其与平滑肌肉瘤的生物学行为、免疫细胞环境和生存的关系

Simon Adrian Georg, Lyu Su Ir, Schultheis Anne Maria, Stahl David, Wuerdemann Nora, Walter Sebastian, Hieggelke Lena, Buettner Reinhard, Bruns Christiane Josephine, Eysel Peer, Schiffmann Lars Mortimer, Knipper Karl, Mallmann Peter, Quaas Alexander, Ullrich Roland

Loss of Argininosuccinate Synthetase-1 (ASS1) Occurs in Esophageal Adenocarcinoma and Represents a Promising Biomarker for Therapy with Pegargiminase

食管腺癌中精氨酸琥珀酸合成酶-1 (ASS1) 的缺失是一种有前景的培加吉明酶治疗生物标志物。

Knipper, Karl; Lyu, Su Ir; Tzitzili, Eleni; Spielmann, Sarah-Michele; Bruns, Christiane J; Schmidt, Thomas; Popp, Felix C; Quaas, Alexander

Expression patterns of TROP2 and Nectin-4 in oropharyngeal squamous cell carcinoma in relation to HPV status: potential biomarkers for targeted therapy.

TROP2 和 Nectin-4 在口咽鳞状细胞癌中的表达模式与 HPV 状态的关系:靶向治疗的潜在生物标志物

Klasen Charlotte, Eckel Hans N C, Wuerdemann Nora, Böckelmann Joseph, Knipper Karl, Suchan Malte, Sharaf Kariem, Sharma Shachi Jenny, Abing Helen, Charpentier Arthur, Esser Julia, Hansen Kevin, Mayer Marcel, Jansen Louis, Klußmann Jens Peter, Quaas Alexander, Lyu Su Ir

Basal-like subtype of esophageal adenocarcinoma and it's morphological, molecular and clinical characteristics

食管腺癌基底样亚型及其形态学、分子和临床特征

Lyu, Su Ir; Fretter, Caroline; Hillmer, Axel M; Grothey, Bastian; Hoppe, Sascha; Simon, Adrian Georg; Zander, Thomas; Knipper, Karl; Schroeder, Wolfgang; Bruns, Christiane J; Quaas, Alexander

MDM2-amplified esophageal adenocarcinomas exhibit an activated metabolic and immunosuppressive phenotype with multiple potential therapeutic targets

MDM2扩增的食管腺癌表现出代谢激活和免疫抑制的表型,并具有多个潜在的治疗靶点。

Knipper, Karl; Bruns, Christiane J; Popp, Felix C; Schmidt, Thomas; Grothey, Bastian; Quaas, Alexander; Lyu, Su Ir

Impact of Surgical Margin Distance on Oncologic Outcomes in Vulvar Squamous Cell Carcinoma

手术切缘距离对阴唇鳞状细胞癌肿瘤学预后的影响

Lenz, Caroline; Lyu, Su Ir; Mallmann, Peter; Morgenstern, Bernd; Thangarajah, Fabinshy