Intestinal interleukin-22 enhances GLP-1 production via the STAT3 pathway to improve glucose homeostasis during high-fat diet induced obesity in a study with male mice.
一项针对雄性小鼠的研究表明，肠道白细胞介素-22 通过 STAT3 通路增强 GLP-1 的产生，从而改善高脂饮食诱导肥胖期间的葡萄糖稳态。
期刊:Nature Communications
影响因子:15.7
doi:10.1038/s41467-026-69734-0
Kim Chae-Won, Ahn Jae-Hee, Lee Bo Ra, Kim Hong Min, Han Youngjoo, Jeong Jae-Hyeon, Cho Jaewon, Jeong Hyunjin, Kim Dae-Joon, Kim Seong-Eun, Kim Jeon-Kyung, Lee Yu-Bin, Kim Su Min, Yoo Hye Hyun, Lee Eun Hye, Seo Su Ryeon, Ha Kyung Bong, Lee Eun Soo, Kweon Mi-Na, Kim Hong Pyo, Chang Sun-Young, Chung Choon Hee, Ko Hyun-Jeong
GLP-1
JAK/STAT
信号转导
代谢
STAT3
肥胖
细胞生物学
