A two-amino-acid substitution in the transcription factor RORγt disrupts its function in TH17 differentiation but not in thymocyte development
转录因子 RORγt 中的两个氨基酸替代会破坏其在 TH17 分化中的作用,但不会影响胸腺细胞发育
期刊:Nature Immunology
影响因子:27.7
doi:10.1038/ni.3832
Zhiheng He, Jian Ma, Ruiqing Wang, Jing Zhang, Zhaofeng Huang, Fei Wang, Subha Sen, Ellen V Rothenberg, Zuoming Sun